ArticleBMC bioinformatics2019
BioVR: a platform for virtual reality assisted biological data integration and visualization.
Article in BMC bioinformatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Effective data visualization strategies in untargeted metabolomics.Natural product reports · 2025Review
- VisionMol: a novel virtual reality tool for protein molecular structure visualization and manipulation.Bioinformatics (Oxford, England) · 2025Article
- Article
- Applications of the metaverse in medicine and healthcare.Advances in laboratory medicine · 2024Review
- Exocentric and Egocentric Views for Biomedical Data Analytics in Virtual Environments-A Usability Study.Journal of imaging · 2023Article
- Technologies for whole-cell modeling: Genome-wide reconstruction of a cell in silico.Development, growth & differentiation · 2023Review
- Metaverse Wearables for Immersive Digital Healthcare: A Review.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Review
- Extended reality for biomedicine.Nature reviews. Methods primers · 2023Article
- Ten simple rules for running a summer research program.PLoS computational biology · 2022Article
- Virtual reality for the observation of oncology models (VROOM): immersive analytics for oncology patient cohorts.Scientific reports · 2022Article
- A Brave New World: Virtual Reality and Augmented Reality in Systems Biology.Frontiers in bioinformatics · 2022Article
- Challenges of intracellular visualization using virtual and augmented reality.Frontiers in bioinformatics · 2022Article
- A Novel Gesture-Based Control System for Fluorescence Volumetric Data in Virtual Reality.Sensors (Basel, Switzerland) · 2021Article
- Pepblock Builder VR - An Open-Source Tool for Gaming-Based Bio-Edutainment in Interactive Protein Design.Frontiers in bioengineering and biotechnology · 2021Article
- ProteinVR: Web-based molecular visualization in virtual reality.PLoS computational biology · 2020Article
- BigTop: a three-dimensional virtual reality tool for GWAS visualization.BMC bioinformatics · 2020Article
- An immersive journey to the molecular structure of SARS-CoV-2: Virtual reality in COVID-19.Computational and structural biotechnology journal · 2020Review
- Virtual Reality for Information Visualization Might Just Work This Time.Frontiers in robotics and AI · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundFunctional characterization of single nucleotide variants (SNVs) involves two steps, the first step is to convert DNA to protein and the second step is to visualize protein sequences with their structures. As massively parallel sequencing has emerged as a leading technology in genomics, resulting in a significant increase in data volume, direct visualization of SNVs together with associated protein sequences/structures in a new user interface (UI) would be a more effective way to assess their potential effects on protein function.
resultsWe have developed BioVR, an easy-to-use interactive, virtual reality (VR)-assisted platform for integrated visual analysis of DNA/RNA/protein sequences and protein structures using Unity3D and the C# programming language. It utilizes the cutting-edge Oculus Rift, and Leap Motion hand detection, resulting in intuitive navigation and exploration of various types of biological data. Using Gria2 and its associated gene product as an example, we present this proof-of-concept software to integrate protein and nucleic acid data. For any amino acid or nucleotide of interest in the Gria2 sequence, it can be quickly linked to its corresponding location on Gria2 protein structure and visualized within VR.
conclusionsUsing innovative 3D techniques, we provide a VR-based platform for visualization of DNA/RNA sequences and protein structures in aggregate, which can be extended to view omics data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.