Evidence map›Paper›PMID 30767767›Full record

ArticleBMC endocrine disorders2019

Frequency and risk factors for recurrent gestational diabetes mellitus in primiparous women: a case control study.

Yin-Yu Wang, Ye Liu, Cheng Li, Jing Lin, Xin-Mei Liu, Jian-Zhong Sheng, He-Feng Huang

Open access · goldAbstract read
In one paragraph

Article in BMC endocrine disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  9. Observational
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  16. Review
  17. Prevalence, Prevention, and Lifestyle Intervention of Gestational Diabetes Mellitus in China.International journal of environmental research and public health · 2020
    Review
  18. Observational
  19. Gestational Diabetes Mellitus: A Harbinger of the Vicious Cycle of Diabetes.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Yin-Yu WangThe International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, No. 1961, Huashan Road, Shanghai, 200030, China.
Ye LiuThe International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, No. 1961, Huashan Road, Shanghai, 200030, China.
Cheng LiThe International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, No. 1961, Huashan Road, Shanghai, 200030, China.
Jing LinThe International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, No. 1961, Huashan Road, Shanghai, 200030, China.
Xin-Mei LiuThe International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, No. 1961, Huashan Road, Shanghai, 200030, China.
Jian-Zhong ShengDepartment of Pathophysiology, Zhejiang University School of Medicine, Hangzhou, 310058, People's Republic of China.
He-Feng HuangThe International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, No. 1961, Huashan Road, Shanghai, 200030, China. huanghefg@sjtu.edu.cn.ORCID http://orcid.org/0000-0002-0195-985X
Shanghai Jiao Tong University · CNInternational Peace Maternity & Child Health Hospital · CNZhejiang University · CN

Funding

Doctoral Innovation Fund of Shanghai Jiao Tong University School of Medicine(CN) BXJ201640National Natural Science Foundation of China 81661128010
6 · The paper itself

Abstract

backgroundTo investigate the frequency and risk factors for recurrent gestational diabetes mellitus (GDM) in Chinese primiparous women.

methodsCase control study. We investigated primiparous women who experienced GDM complications and had a subsequent pregnancy in the same hospital from January, 2012 to January, 2017. Ultimately, 78 women with recurrent GDM and 64 women with no recurrence were included. Clinical characteristics and biochemical parameters such as fasting plasma glucose (FPG), oral glucose tolerance test (OGTT) and lipid profiles were collected from medical records. We used an independent t-test and Chi-square test or Fisher's exact test to compare each variable. Univariate and multivariate logistic analyses were used to compute each odds ratio (OR) and 95% confidence interval (CI).

resultsThe frequency of recurrent GDM was 55%. We found postprandial 1-h glucose at the 75-g OGTT was positively related to GDM recurrence, whereas first-trimester FPG in first pregnancy was negatively related. The first-trimester HbA1c value was higher in the group with GDM recurrence than in the group with no recurrence, though the difference was not significant. Moreover, the group with GDM recurrence manifested significantly higher first-trimester triglyceride concentrations in subsequent pregnancies; the adjusted ORs (95% CI) were 1.43 (1.09-1.87), 0.24 (0.10-0.63), 3.59 (0.93-13.88) and 1.89 (1.13-3.16).

conclusionsGDM recurred in more than half of subsequent pregnancies. Women with lower first-trimester FPG and higher postprandial 1-h glucose in first pregnancy, and with higher first-trimester triglyceride in subsequent pregnancy were at increased risk for GDM recurrence.

Indexed as

ParityAdultBiomarkersChinaDiabetes, GestationalFemaleFollow-Up StudiesHumansIncidencePregnancyPrognosisRecurrenceRisk FactorsBiomarkersBiochemical parameterChinese primiparous womanGestational diabetes mellitusRecurrenceRisk factor

Identifiers

PMID30767767
PMCPMC6377747
OpenAlexW2921255924

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.