Evidence map›Paper›PMID 30767430›Full record

ArticleCancer medicine2019

The clinical implication of CD45RA

Junjie Hang, Junjie Huang, Siyuan Zhou, Lixia Wu, Yingwei Zhu, Lina Zhu, Hanyu Zhou, Kequn Xu, Hua Jiang, Xuguang Yang

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  7. In-vitro model to mimic T cell subset change in human PDAC organoid co-culture.Journal of cancer research and clinical oncology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Immunosenescence in Aging-Related Vascular Dysfunction.International journal of molecular sciences · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. The clinical implication of CD45RACancer medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Junjie HangDepartment of Oncology, Changzhou No.2 People's Hospital, Affiliated Hospital of Nanjing Medical University, Changzhou, Jiangsu, China.
Junjie HuangJC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China.
Siyuan ZhouDepartment of Oncology, Changzhou No.2 People's Hospital, Affiliated Hospital of Nanjing Medical University, Changzhou, Jiangsu, China.
Lixia WuDepartment of Oncology, Shanghai JingAn District ZhaBei Central Hospital, Shanghai, China.
Yingwei ZhuDepartment of Oncology, Changzhou No.2 People's Hospital, Affiliated Hospital of Nanjing Medical University, Changzhou, Jiangsu, China.
Lina ZhuDepartment of Oncology, Changzhou No.2 People's Hospital, Affiliated Hospital of Nanjing Medical University, Changzhou, Jiangsu, China.
Hanyu ZhouDepartment of Oncology, Changzhou No.2 People's Hospital, Affiliated Hospital of Nanjing Medical University, Changzhou, Jiangsu, China.
Kequn XuDepartment of Oncology, Changzhou No.2 People's Hospital, Affiliated Hospital of Nanjing Medical University, Changzhou, Jiangsu, China.
Hua JiangDepartment of Oncology, Changzhou No.2 People's Hospital, Affiliated Hospital of Nanjing Medical University, Changzhou, Jiangsu, China.
Xuguang YangState Key Laboratory for Oncogenes and Related Genes, Department of Oncology, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Changzhou No.2 People's Hospital · CNNanjing Medical University · CNChinese University of Hong Kong · CNRenji Hospital · CNShanghai Zhabei District Shibei Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Naïve and memory T cells play a pivotal role in solid tumor pathogenesis but their role in pancreatic cancer progression remains elusive. Thus, we aimed to investigate their clinical potential in advanced pancreatic cancer (APC). Flow cytometry was performed to evaluate the level of baseline peripheral naïve and memory T cells from 137 APC patients before receiving first-line chemotherapy. Interrelationships between naïve, memory T cells and clinicopathological variables were evaluated using Pearson's correlation. The prognostic impact of naïve and memory T cells were assessed by Kaplan-Meier analysis and Cox regression. The correlation between naïve/memory T cells and tumor progression was investigated by Student's t test. CD4

Indexed as

Immunologic MemoryAdultAgedAged, 80 and overBiomarkersDisease ProgressionFemaleHumansImmunophenotypingKaplan-Meier EstimateLeukocyte Common AntigensLymphocyte CountMaleMiddle AgedNeoplasm MetastasisNeoplasm StagingBiomarkersLeukocyte Common Antigensadvanced pancreatic cancermemory T cellsnaïve T cellsprognostic valueprogression prediction

Identifiers

PMID30767430
PMCPMC6434335
OpenAlexW2914435722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.