Evidence map›Paper›PMID 30767377›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2019

Impact on renal resistive index of diabetes in renal transplant donors and recipients: A retrospective analysis of 1827 kidney transplant recipients.

Jean-Baptiste de Freminville, Louis-Marie Vernier, Jérome Roumy, Frédéric Patat, Philippe Gatault, Bénédicte Sautenet, Elodie Bailly, Eloi Chevallier, Christelle Barbet, Hélène Longuet and 4 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Jean-Baptiste de FreminvilleNéphrologie-Immunologie Clinique, Hôpital Bretonneau, CHRU Tours, Tours, France.ORCID 0000-0003-3829-9506
Louis-Marie VernierNéphrologie-Dialyses, Hopital Caremeau, Nimes, France.
Jérome RoumyImagerie Médicale, Hôpital Bretonneau, CHRU Tours, Tours, France.
Frédéric PatatImagerie Médicale, Hôpital Bretonneau, CHRU Tours, Tours, France.
Philippe GataultNéphrologie-Immunologie Clinique, Hôpital Bretonneau, CHRU Tours, Tours, France.
Bénédicte SautenetNéphrologie-Immunologie Clinique, Hôpital Bretonneau, CHRU Tours, Tours, France.
Elodie BaillyNéphrologie-Immunologie Clinique, Hôpital Bretonneau, CHRU Tours, Tours, France.
Eloi ChevallierNéphrologie-Immunologie Clinique, Hôpital Bretonneau, CHRU Tours, Tours, France.
Christelle BarbetNéphrologie-Immunologie Clinique, Hôpital Bretonneau, CHRU Tours, Tours, France.
Hélène LonguetNéphrologie-Immunologie Clinique, Hôpital Bretonneau, CHRU Tours, Tours, France.
Elodie MerieauNéphrologie-Immunologie Clinique, Hôpital Bretonneau, CHRU Tours, Tours, France.
Christophe BaronNéphrologie-Immunologie Clinique, Hôpital Bretonneau, CHRU Tours, Tours, France.
Matthias BuchlerNéphrologie-Immunologie Clinique, Hôpital Bretonneau, CHRU Tours, Tours, France.
Jean-Michel HalimiNéphrologie-Immunologie Clinique, Hôpital Bretonneau, CHRU Tours, Tours, France.
Centre Hospitalier Universitaire de Tours · FRUniversité de Tours · FRCentre Hospitalier Universitaire de Nîmes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High renal resistive index (RI) is observed in diabetes and is associated with poor patient survival, but whether it is primarily due to renal vascular resistance or systemic vascular alterations is unclear. The respective impact of kidney transplant from diabetic donors or to diabetic recipients on RI would shed some light on this issue. The objective of the study was to analyze the impact of donor and recipient diabetes on RI in order to understand the respective impact of the kidney and the vascular environment. The authors conducted a retrospective study in 1827 renal transplant recipients who received a kidney between 1985 and 2017, and had Doppler measurements at 3 months after transplant. Donor and recipient characteristics at the time of transplant and at 3 months were reviewed. Both donor diabetes and recipient diabetes were associated with RI in univariate analysis, but only recipient diabetes remained significantly associated in stepwise multivariate analyses (effect estimate on RI: +0.03 ± 0.005, P < 0.001). These findings were confirmed when RI was expressed as a binary variable using a cutoff of 0.75 (OR = 2.50 [1.77, 3.54], P < 0.001). Other determinants of RI were recipient characteristics (age, sex, systolic and diastolic blood pressure, and duration of dialysis). Donor characteristics were not associated with RI. Our results suggest that high RI observed in diabetic recipients shortly after transplant is primarily due to the new vascular environment, rather than to characteristics of the transplanted kidney. Therefore, RI reflects systemic rather than intra-renal changes.

Indexed as

AdultAgedAlgorithmsBlood PressureCreatinineDelayed Graft FunctionDiabetes MellitusFemaleFranceGlomerular Filtration RateHumansKidneyKidney TransplantationMaleMiddle AgedProteinuriaCreatininediabetes mellituskidney transplantrenal resistive indexultrasonographyvascular resistance

Identifiers

PMID30767377
PMCPMC8030490
OpenAlexW2913090827

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.