SynthesisClinical oral investigations2019
Different light-activation systems associated with dental bleaching: a systematic review and a network meta-analysis.
Synthesis in Clinical oral investigations, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparative efficacy of violet light, bleaching gel, or their combination, in in-office bleaching: a systematic review and network meta-analysis.Brazilian oral research · 2026Pooled it
- Bleaching efficacy and tooth sensitivity using violet LED - single-blind randomized controlled trial.Lasers in medical science · 2025Trial
- Tooth Sensitivity Following Hydrogen Peroxide Bleaching With and Without Ozone: A Randomized Controlled Trial: Tooth Sensitivity Following HPain research & management · 2024Trial
- Colorimetric evaluation after in-office tooth bleaching with violet LED: 6- and 12-month follow-ups of a randomized clinical trial.Clinical oral investigations · 2022Trial
- Triple-blinded randomized clinical trial comparing efficacy and tooth sensitivity of in-office and at-home bleaching techniques.Journal of applied oral science : revista FOB · 2021Trial
- Effect of violet LED light on in-office bleaching protocols: a randomized controlled clinical trial.Journal of applied oral science : revista FOB · 2020Trial
- Evaluation of different internal bleaching methods after application of two bioceramic formulations in revascularization treatment: an in vitro study.Scientific reports · 2026Article
- Effect of violet and blue light activation on in-office bleaching with 6% hydrogen peroxide: color change, penetration into the pulp chamber and bleaching gel stability.Lasers in medical science · 2026Article
- Microhardness Recovery Kinetics, Surface Roughness Trajectories, and Erosive Wear Susceptibility of Enamel After Three In-Office Bleaching Protocols: A 28-Day In Vitro Investigation.Dentistry journal · 2026Article
- Clinical myths in dental bleaching: an evidence-based structured narrative review.Brazilian oral research · 2026Review
- Enamel Surface and Elemental Changes Following In Vitro Bleaching: A SEM-EDS Approach.Dentistry journal · 2025Article
- Low and high hydrogen peroxide concentrations of in-office dental bleaching associated with violet light: an in vitro study.Clinical oral investigations · 2024Article
- Comparison of in-office and at-home bleaching techniques: An umbrella review of efficacy and post-operative sensitivity.Heliyon · 2024Article
- Effectiveness of violet LED with or without a bleaching gel: a 12-month randomized clinical trial.Frontiers in dental medicine · 2024Article
- Treatment Durations and Whitening Outcomes of Different Tooth Whitening Systems.Medicina (Kaunas, Lithuania) · 2023Article
- Titanium dioxide nanotubes in a hydrogen peroxide-based bleaching agent: physicochemical properties and effectiveness of dental bleaching under the influence of a poliwave led light activation.Clinical oral investigations · 2023Article
- Effect of endodontic sealer on postoperative pain: a network meta-analysis.Restorative dentistry & endodontics · 2023Review
- In-office dental bleaching with violet light emitting diode: bleaching efficacy and pulpal temperature rise.Restorative dentistry & endodontics · 2022Article
- Effect of Polishing on the Surface Microhardness of Nanohybrid Composite Resins Subjected to 35% Hydrogen Peroxide: AnJournal of International Society of Preventive & Community DentistryArticle
- Influence of light and laser activation of tooth bleaching systems on enamel microhardness and surface roughness.Journal of conservative dentistry : JCDArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectivesA systematic review and a network meta-analysis were performed to answer the following research question: "Is there any light-activation protocol capable of improving color change efficacy when associated with an in-office bleaching gel in adults?" MATERIAL AND
methodsA search was performed in PubMed, Scopus, Web of Science, LILACS, BBO, Cochrane Library, and SIGLE without date and/or language restrictions in April 23, 2017 (updated on March 30, 2018). IADR abstracts (1990-2018), unpublished and ongoing trial registries, dissertations, and theses were also searched. Only randomized clinical trials conducted in adults that included at least one group treated with in-office dental bleaching with light activation were included. The risk of bias (RoB) was evaluated using the Cochrane Collaboration tool. A random-effects Bayesian-mixed treatment comparison (MTC) model was used to combine light-activated versus light-free in-office bleaching with direct light-free comparison trials. A meta-analysis with independent analysis (high- and low-concentrate hydrogen peroxide [HP]) was conducted for color change (∆E*, ∆SGU).
resultsAfter the removal of duplicates, title, and abstract screening, 28 studies remained. Nine were considered to be at a low RoB, five were at a high RoB, and the remaining were at an unclear RoB. The MTC analysis showed no significant difference in color change (ΔE* and ΔSGU) between light-activation protocols and light-free in-office bleaching, regardless of the HP concentration in the efficacy of the bleaching.
conclusionNo type of light-activated in-office bleaching was superior to light-free in-office bleaching for both high- and low-concentrate in-office bleaching gels (PROSPERO-CRD42017078743). CLINICAL RELEVANCE: Although many times dental professionals use "laser whitening" as a form of marketing, this study confirmed that no type of light-activation for in-office bleaching can improve the bleaching efficacy.
Indexed as
Identifiers
30767069What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.