Evidence map›Paper›PMID 30767067›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2019

Meniscal allograft transplantation: undersizing grafts can lead to increased rates of clinical and mechanical failure.

Ciara Stevenson, Ahmed Mahmoud, Francois Tudor, Peter Myers

Abstract read
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In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Three-dimensional meniscus allograft sizing-a study of 280 healthy menisci.Journal of orthopaedic surgery and research · 2020
    Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Autologous semitendinosus tendon graft could function as a meniscal transplant.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022
    Article
  14. Review
  15. Review
  16. Meniscal allograft transplantation: a review of indications, techniques, and outcomes.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020
    Review
  17. Risk of Subsequent Knee Arthroplasty After Sports Medicine Procedures.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2020
    Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ciara StevensonBrisbane Orthopaedic and Sports Medicine Centre, Level 6 Brisbane Private Hospital, 259 Wickham Terrace, Brisbane, QLD, Australia. stevensonciara@yahoo.co.uk.ORCID http://orcid.org/0000-0002-3334-9693
Ahmed MahmoudBrisbane Orthopaedic and Sports Medicine Centre, Level 6 Brisbane Private Hospital, 259 Wickham Terrace, Brisbane, QLD, Australia.
Francois TudorBrisbane Orthopaedic and Sports Medicine Centre, Level 6 Brisbane Private Hospital, 259 Wickham Terrace, Brisbane, QLD, Australia.
Peter MyersBrisbane Orthopaedic and Sports Medicine Centre, Level 6 Brisbane Private Hospital, 259 Wickham Terrace, Brisbane, QLD, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess mid-term survivorship of meniscal allograft transplantation (MAT) and determine the effect that pre-operative meniscal sizing has upon functional outcome and mechanical survivorship.

methodsA prospectively collected database of patients receiving MAT from 2001 to 2017 was analysed. Data include demographics; sizing measurements, complications, further surgery, and patient-reported outcome measures (PROMs). Allografts were fresh frozen, non-irradiated, and sized using the Pollard technique.

resultsSeventy-three MATs were performed in 67 patients; mean age at MAT was 34 years (range 14-52 years). 56% were male and 62% were medial. The mean follow-up was 75 months (6.25 years). Mechanical survival at 5 and 10 years was 96% and 89.4%, respectively. There were statistically significant improvements in all PROMs; mean Lysholm score improved by 17.5 points [95% confidence interval (CI) 22.2-12.9, p < 0.001]; mean IKDC score improved significantly by 13.3 points (CI 19.3-7.4, p < 0.001); mean OKS improved by 5.6 points (CI 9.2-2.2, p < 0.002); and the median Tegner improved by 1 point. Forty-one MATs (56%) were undersized for width (range 1-11 mm). Seven MATs (10%) were undersized for length (range 1-4 mm). There was no statistically significant difference in mechanical survivorship or clinical outcomes between undersized, matched, or oversized grafts overall; however, sub-group analysis demonstrated increased failure when allografts were undersized by more than 5 mm in width.

conclusionsMAT is an effective treatment to improve function and alleviate pain with excellent survivorship in this series. Accepting an allograft that is more than 5 mm smaller in width than pre-operative templating increases the likelihood of clinical and mechanical failure. We, therefore, urge surgeons to be familiar with the measuring process used by their individual tissue bank provider to avoid graft-host mismatch that could affect outcome.

Indexed as

AllograftsGraft SurvivalPatient Reported Outcome MeasuresAdolescentAdultFemaleFollow-Up StudiesHumansMaleMenisci, TibialMiddle AgedProspective StudiesTibial Meniscus InjuriesYoung AdultAllograftMeniscusPatient-reported outcome measureSizingSurvivorshipTransplant

Identifiers

PMID30767067

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.