Evidence map›Paper›PMID 30766965›Full record

ArticleHepatology communications2019

Yun Zhou, Vatsalya Vatsalya, Leila Gobejishvili, Richard J Lamont, Craig J McClain, Wenke Feng

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Hepatology communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05178069 (Lactobacillus Rhamnosus GG), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05178069 phase2recruitingnot on this mapstarted 2022, after this paper: background citation

Lactobacillus Rhamnosus GG: A Novel Probiotic Therapy for Treating Alcohol Use Disorder

TypeinterventionalSponsorUniversity of LouisvilleRan2022 to 2027Enrolled60ConditionsAlcohol Use Disorder, Alcohol-associated Liver DiseaseArms: Placebo for Probiotic, Lactobacillus Rhamnosus GG
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Frontiers in microbiology · 2025
    Article
  3. Review
  4. Role of Oral Health, Frailty, and Minimal Hepatic Encephalopathy in the Risk of Hospitalization: A Prospective Multi-Center Cohort of Outpatients With Cirrhosis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Microbiome dysbiosis and alcoholic liver diseaseLiver research (Beijing, China) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yun ZhouDepartment of Medicine University of Louisville Louisville KY.
Vatsalya VatsalyaDepartment of Medicine University of Louisville Louisville KY.
Leila GobejishviliDepartment of Medicine University of Louisville Louisville KY.
Richard J LamontDepartment of Oral Immunology and Infectious Diseases University of Louisville Louisville KY.
Craig J McClainDepartment of Medicine University of Louisville Louisville KY.
Wenke FengDepartment of Medicine University of Louisville Louisville KY.
University of Louisville · USLouisville VA Medical Center · US

Funding

Role of oxidized linoleic acid metabolites in the pathogenesis of alcoholic liver diseaseP20GM113226 · NIGMS · UNIVERSITY OF LOUISVILLE · PI MCCLAIN, CRAIG J. · 2016 to 2025
$24.1M
The Role of Nutrition in the Development/Progression of Alcohol-Induced Organ InjuryP50AA024337 · NIAAA · UNIVERSITY OF LOUISVILLE · PI SHIRISH S BARVE · 2016 to 2026
$17.9M
Novel Therapies for Alcoholic HepatitisU01AA021893 · NIAAA · CLEVELAND CLINIC LERNER COM-CWRU · PI MCCLAIN, CRAIG J., MCCULLOUGH, ARTHUR JOSEPH · 2012 to 2017
$6.0M
Mechanisms of Probiotics in Alcoholic Liver DiseaseR01AA023190 · NIAAA · UNIVERSITY OF LOUISVILLE · PI FENG, WENKE · 2015 to 2024
$3.5M
Oxidized Metabolites of Linoleic Acid in Alcohol-induced Liver InjuryU01AA022489 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FELDSTEIN, ARIEL, MCCLAIN, CRAIG J. · 2014 to 2018
$1.7M
Mechanisms for alcohol induced gut barrier dysfunction in ALDR01AA023681 · NIAAA · UNIVERSITY OF LOUISVILLE · PI MCCLAIN, CRAIG J. · 2014 to 2018
$1.6M
Novel therapies in alcoholic hepatitis University of LouisvilleU01AA021901 · NIAAA · UNIVERSITY OF LOUISVILLE · PI MCCLAIN, CRAIG J. · 2012 to 2017
$1.5M
Lipid metabolites can both potentiate and treat alcoholic hepatitisU01AA026936 · NIAAA · UNIVERSITY OF LOUISVILLE · PI JOSHI-BARVE, SWATI, MCCLAIN, CRAIG J. · 2018 to 2022
$1.2M
Probiotics and HIF signaling in Alcoholic Liver DiseaseR21AA020848 · NIAAA · UNIVERSITY OF LOUISVILLE · PI FENG, WENKE · 2013 to 2014
$376k
Dietary Fat and Alcoholic Liver DiseaseI01BX002996 · VA · LOUISVILLE VA MEDICAL MEDICAL CENTER · PI MCCLAIN, CRAIG J. · 2017 to 2020
–
BLRD VA I01 BX002996NIAAA NIH HHS P50 AA024337NIAAA NIH HHS R01 AA023190NIAAA NIH HHS R01 AA023681NIAAA NIH HHS R21 AA020848NIAAA NIH HHS U01 AA021893NIAAA NIH HHS U01 AA021901NIAAA NIH HHS U01 AA022489NIAAA NIH HHS U01 AA026936NIGMS NIH HHS P20 GM113226
6 · The paper itself

Abstract

Bacterial infection is frequently observed in patients with alcoholic liver disease (ALD). We examined a possible role of

Identifiers

PMID30766965
PMCPMC6357836
OpenAlexW2904855182

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.