Evidence map›Paper›PMID 30766961›Full record

ArticleHepatology communications2019

Intestine-Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet-Induced Liver Steatosis and Obesity.

Lisa Katharina Maresch, Pia Benedikt, Ursula Feiler, Sandra Eder, Kathrin A Zierler, Ulrike Taschler, Stephanie Kolleritsch, Thomas O Eichmann, Gabriele Schoiswohl, Christina Leopold and 8 more

Open access · goldAbstract read
In one paragraph

Article in Hepatology communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. RNA-seq analysis reveals transcriptome changes in livers fromBiochemistry and biophysics reports · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Enterocyte-specific ATGL overexpression affects intestinal and systemic cholesterol homeostasis.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2022
    Article
  11. Review
  12. Article
  13. Hepatocyte-specific expression of human carboxylesterase 2 attenuates nonalcoholic steatohepatitis in mice.American journal of physiology. Gastrointestinal and liver physiology · 2021
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

Lisa Katharina MareschInstitute of Molecular Biosciences University of Graz Graz Austria.
Pia BenediktInstitute of Molecular Biosciences University of Graz Graz Austria.
Ursula FeilerInstitute of Molecular Biosciences University of Graz Graz Austria.
Sandra EderInstitute of Molecular Biosciences University of Graz Graz Austria.
Kathrin A ZierlerInstitute of Molecular Biosciences University of Graz Graz Austria.
Ulrike TaschlerInstitute of Molecular Biosciences University of Graz Graz Austria.
Stephanie KolleritschInstitute of Molecular Biosciences University of Graz Graz Austria.
Thomas O EichmannInstitute of Molecular Biosciences University of Graz Graz Austria.
Gabriele SchoiswohlInstitute of Molecular Biosciences University of Graz Graz Austria.
Christina LeopoldGottfried Schatz Research Center, Molecular Biology and Biochemistry Medical University of Graz Graz Austria.
Beatrix I WieserDiagnostic & Research Center for Molecular BioMedicine Institute of Pathology Medical University of Graz Graz Austria.
Caroline LacknerDiagnostic & Research Center for Molecular BioMedicine Institute of Pathology Medical University of Graz Graz Austria.
Thomas RülickeInstitute of Laboratory Animal Science University of Veterinary Medicine Wien Austria.
Jan van KlinkenDepartment of Human Genetics Leiden University Medical Centre Leiden the Netherlands.
Dagmar KratkyGottfried Schatz Research Center, Molecular Biology and Biochemistry Medical University of Graz Graz Austria.
Tarek MoustafaDivision of Gastroenterology and Hepatology Medical University Graz Graz Austria.
Gerald HoeflerDiagnostic & Research Center for Molecular BioMedicine Institute of Pathology Medical University of Graz Graz Austria.
Guenter HaemmerleInstitute of Molecular Biosciences University of Graz Graz Austria.
University of Graz · ATMedical University of Graz · ATLeiden University · NLUniversity of Veterinary Medicine Vienna · AT

Funding

Lipid profile, lipoprotein and apolipoprotein composition, and intestinal fat absorption efficiency in germ-free and conventional miceU2CDK059630 · NIDDK · UNIVERSITY OF CINCINNATI · PI LIU, MIN · 2016 to 2021
$4.9M
Austrian Science Fund FWF P 28882NIDDK NIH HHS U2C DK059630
6 · The paper itself

Abstract

Murine hepatic carboxylesterase 2c (

Identifiers

PMID30766961
PMCPMC6357831
OpenAlexW2904108146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.