Evidence map›Paper›PMID 30766955›Full record

ArticleHepatology communications2019

Intestinal Lipolysis Mitigates Nonalcoholic Fatty Liver Disease: New Roles for Carboxylesterase 2c in the Intestine.

Michael Pimienta, Alexander Beletsky, Ekihiro Seki

Open access · goldAbstract readEditorial
In one paragraph

Article in Hepatology communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Michael PimientaUniversity of California, San Diego, School of Medicine La Jolla CA.
Alexander BeletskyUniversity of California, San Diego, School of Medicine La Jolla CA.
Ekihiro SekiDivision of Digestive and Liver Diseases, Department of Medicine Cedars-Sinai Medicine Center Los Angeles CA.ORCID https://orcid.org/0000-0002-9472-6085
Cedars-Sinai Medical Center · USUniversity of California San Diego · US

Funding

LPS binding to TLR4 regulates hepatic stellate cell activation and fibrosisR01DK085252 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI EKIHIRO SEKI · 2011 to 2026
$4.8M
S-Adenosylmethionine in Protein Posttranslational Modifications and HCC TreatmentR01DK107288 · NIDDK · CEDARS-SINAI MEDICAL CENTER · PI LU, SHELLY CHI-LOO · 2015 to 2018
$1.6M
Alcohol enhances colon cancer liver metastasis via cancer-associated fibroblastsR21AA025841 · NIAAA · CEDARS-SINAI MEDICAL CENTER · PI SEKI, EKIHIRO · 2017 to 2018
$459k
NIAAA NIH HHS R21 AA025841NIDDK NIH HHS R01 DK085252NIDDK NIH HHS R01 DK107288
6 · The paper itself

Abstract

The most important argument of this study is that modulation of intestinal lipid metabolism by enhancing intestinal

Identifiers

PMID30766955
PMCPMC6357825
OpenAlexW2914140540

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.