ArticleActa pharmaceutica Sinica. B2019
Advances in coamorphous drug delivery systems.
Article in Acta pharmaceutica Sinica. B, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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Who cites it
57 citing papers in PubMed.
- Co-amorphization for solubility and dissolution rate improvement: the case of low-crystallization-tendency drugs.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026Review
- The Application of Machine Learning in the Development of Co-Amorphous Dry Powder Inhalation.AAPS PharmSciTech · 2026Article
- Crystal engineering for poorly water-soluble drugs: From design to applications.Acta pharmaceutica Sinica. B · 2026Review
- Entropy-mediated solidification stabilizes and enhances energetic release in amorphous energetic materials.Nature communications · 2026Article
- Two Drug-Drug Co-Amorphous Systems of Curcumin and Berberine Hydrochloride/Palmatine Hydrochloride with Improved Physicochemical Properties and Multifunctional Activities.Pharmaceutics · 2025Article
- Comparative evaluation of ternary amorphous solid dispersions: Identifying optimal excipient systems for enhancing drug solubility.International journal of pharmaceutics: X · 2025Review
- Enhanced solubility and bioavailability of coenzyme Q10 via co-amorphous system using stevioside.NPJ science of food · 2025Article
- Preparation and Characterization of Vitamin D3-Based Binary Amorphous Systems.Foods (Basel, Switzerland) · 2025Article
- Long-Term Stabilized and Highly Soluble Bezafibrate-Gliclazide Co-Amorphous Binary System.AAPS PharmSciTech · 2025Article
- Stability of Ternary Drug-Drug-Drug Coamorphous Systems Obtained Through Mechanochemistry.Pharmaceutics · 2025Article
- Enhancing the Solubility of Co-Formulated Hydrophobic Drugs by Incorporating Functionalized Nano-Structured Poly Lactic-Pharmaceutics · 2025Article
- Considerations and Challenges to Develop Drug-drug Coamorphous System: A Recent Update.Current pharmaceutical biotechnology · 2025Review
- Preparation, Characterization and Evaluation of Nintedanib Amorphous Solid Dispersions with Enhanced Oral Bioavailability.AAPS PharmSciTech · 2024Article
- System-agnostic prediction of pharmaceutical excipient miscibility via computing-as-a-service and experimental validation.Scientific reports · 2024Article
- Preparation and Characterization of Lutein Co-Amorphous Formulation with Enhanced Solubility and Dissolution.Foods (Basel, Switzerland) · 2024Article
- Screening of Organic Small Molecule Excipients on Ternary Solid Dispersions Based on Miscibility and Hydrogen Bonding Analysis: Experiments and Molecular Simulation.AAPS PharmSciTech · 2024Article
- Drug-Coformer Loaded-Mesoporous Silica Nanoparticles: A Review of the Preparation, Characterization, and Mechanism of Drug Release.International journal of nanomedicine · 2024Review
- Influence of Crystal Disorder on the Forced Oxidative Degradation of Vortioxetine HBr.AAPS PharmSciTech · 2023Article
- Amorphization of Low Soluble Drug with Amino Acids to Improve Its Therapeutic Efficacy: a State-of-Art-Review.AAPS PharmSciTech · 2023Review
- Coformer-Dependent Physical Stability in a Series of Naringenin-Based Coamorphous Materials with Caffeine, Theophylline, and Theobromine.Pharmaceutical research · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, the coamorphous drug delivery system has been established as a promising formulation approach for delivering poorly water-soluble drugs. The coamorphous solid is a single-phase system containing an active pharmaceutical ingredient (API) and other low molecular weight molecules that might be pharmacologically relevant APIs or excipients. These formulations exhibit considerable advantages over neat crystalline or amorphous material, including improved physical stability, dissolution profiles, and potentially enhanced therapeutic efficacy. This review provides a comprehensive overview of coamorphous drug delivery systems from the perspectives of preparation, physicochemical characteristics, physical stability,
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.