ArticleAfrican health sciences2018
Evaluation of antibiotic prescriptions and use in under-five children in Ibadan, SouthWestern Nigeria.
Article in African health sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- National and regional challenges of antibiotic prescribing patterns in pediatric populations across Africa: a systematic review and meta-analysis.Systematic reviews · 2026Pooled it
- Prevalence of antibiotics prescription amongst patients with and without COVID-19 in low- and middle-income countries: a systematic review and meta-analysis.Pathogens and global health · 2023Pooled it
- Antibiotic Prescribing in Hospitalized Pediatric Patients Before Implementation of a Syndromic Antibiogram at Maputo Central Hospital, Mozambique.Pediatric reports · 2026Article
- Antimicrobial resistance of bacteria isolated in a resource-limited region: the experience of the North Kivu Provincial Reference Laboratory in the Democratic Republic of the Congo.Frontiers in medicine · 2026Article
- Pattern and appropriateness of antibiotic therapy for acute respiratory tract infection among under-five children accessing care in a tertiary facility, Sokoto, Nigeria.BMJ paediatrics open · 2025Article
- The role of breastfeeding, antibiotics and antimalarial medicinal exposure in paediatric depression amongst children aged under 5: a population-based study.BMC pediatrics · 2025Article
- Correct diagnostic classification and treatment of pneumonia symptoms in under-five children, northwest Ethiopia: a cross-sectional study.BMJ paediatrics open · 2025Article
- Drug-Induced Liver Injury-Pharmacological Spectrum Among Children.International journal of molecular sciences · 2025Review
- Antibiotic prescribing practices according to the AWaRe classification among children under 5 of age attending public primary care centres in four West African countries: a cross-sectional study (AIRE project, 2021-2022).BMJ paediatrics open · 2024Article
- Genomic Characterization of Multidrug-Resistant Pathogenic Enteric Bacteria from Healthy Children in Osun State, Nigeria.Microorganisms · 2024Article
- A Narrative Review of Antibiotic Prescribing Practices in Primary Care Settings in South Africa and Potential Ways Forward to Reduce Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2023Article
- Antibiotic prescribing patterns at children's outpatient departments of primary care institutions in Southwest China.BMC primary care · 2022Article
- Antibiotic use among children under five years with diarrhea in rural communities of Gulu, northern Uganda: a cross-sectional study.BMC public health · 2021Article
- WHO/INRUD core prescribing indicators and antibiotic utilization patterns among primary health care facilities in Ilala district, Tanzania.JAC-antimicrobial resistance · 2021Article
- Evaluating antibiotic use and developing a tool to optimize prescribing in a family-centered HIV clinic in Eswatini.PloS one · 2021Article
- Phenotypic and genotypic characterization of clinical carbapenem-resistantNew microbes and new infections · 2020Article
- Unnecessary antimicrobial prescribing for upper respiratory tract infections in children in Pietermaritzburg, South Africa.African health sciences · 2020Article
- Article
- Interface of non-communicable diseases and infections in Africa.African health sciences · 2018Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIrrational antibiotic prescriptions for children is a global concern requiring periodic evaluation and monitoring.
objectivesTo assess appropriateness of antibiotic prescribing for under-five children, as well as evaluating mothers' usage of antibiotics for their under-five and reason(s) for use.
methodCross-sectional review of out-patient case-notes of under-five using principles of antibiotic prescribing and a questionnaire-guided interaction with under-five mothers.
resultsNearly all (445;98.9%) antibiotic prescriptions were based on signs and symptoms indicative of bacterial infection. Only 3(0.7%) had the initial antibiotic regimen modified. Nine (2.0%) had documented evidence of sensitivity test requested before antibiotic prescribing. Presence of infection or need for antibiotic therapy was established in 190(42.2%). Majority (324;72.0%) of mothers had administered antibiotics to their under-five. Of these, 157(48.5%) were prescribed by physicians and 79(24.4%) were self-recommended. Educational status of mothers significantly influenced antibiotic usage.
conclusionAntibiotic prescriptions for under-fives was largely based on symptoms indicative of bacterial infections, thereby corroborating the widespread empirical antibiotic prescribing. Considerable number of mothers engaged in self-recommendation of antibiotics for their under-fives. Thus, there is a need for continuous enlightenment of prescribers and mothers on rational use of antibiotics, while microbiological confirmation of clinical diagnosis is encouraged for evidence-based antibiotic prescribing.
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