ArticleAfrican health sciences2018
Cytomegalovirus infection among Human Immunodeficiency Virus (HIV) infected individuals on highly active anti-retroviral therapy in North-Central Nigeria.
Article in African health sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 19 citations in OpenAlex.
- Seroprevalence of cytomegalovirus in individuals on antiretroviral therapy in a Nigerian tertiary hospital.BMC infectious diseases · 2026Article
- Immunogenetic Profile Associated with Patients Living with HIV-1 and Epstein-Barr Virus (EBV) in the Brazilian Amazon Region.Viruses · 2024Article
- CMV and HIV Coinfection in Women from a Region in Eastern Europe.Journal of personalized medicine · 2023Article
- Human cytomegalovirus infection among treatment-naive HIV-1 infected patients in Ethiopia.PloS one · 2021Article
- Interface of non-communicable diseases and infections in Africa.African health sciences · 2018Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCytomegalovirus (CMV) infection is common among HIV-infected individuals. Its contribution to morbidity and mortality became more apparent following introduction of highly active anti-retroviral therapy (HAART) which improved survival among HIV-infected individuals.
objectivesThis study aimed at determining the prevalence of both active and latent CMV infections among HIV-infected individuals on HAART in Ilorin, Nigeria.
methodsA total of 360 consented HIV-1 patients were recruited for the study. About 5ml of blood and socio-demographic data were collected from each patient. Plasma from the blood was tested for anti-CMV IgM and IgG presence using ELISA.
resultsOf the 360 participants tested, 42 (11.7%) and 265 (73.6%) were respectively anti-CMV IgM and IgG antibodies positive representing active and latent infection rates respectively. Gender and age were the correlates of IgM seropositivity while age, occupation and marital status correlated with IgG seropositivity. Occupation, marital status, use of HAART and CD4
conclusionsThis study has demonstrated high level of latent and active CMV infection among HAART recipients in Ilorin and highlighted the need for incorporation of anti-herpes drugs in the treatment regimen.
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