Evidence map›Paper›PMID 30766535›Full record

ArticleFrontiers in immunology2019

Humanized Mouse Model Mimicking Pathology of Human Tuberculosis for

Frida Arrey, Delia Löwe, Stefanie Kuhlmann, Peggy Kaiser, Pedro Moura-Alves, Gopinath Krishnamoorthy, Laura Lozza, Jeroen Maertzdorf, Tatsiana Skrahina, Alena Skrahina and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Applications of humanized mice inMolecular medicine reports · 2026
    Review
  2. Article
  3. Experimental dissection of tuberculosis protective immunity: a human perspective.Frontiers in cellular and infection microbiology · 2025
    Review
  4. Review
  5. Article
  6. Immunopathology of PulmonaryInternational journal of molecular sciences · 2024
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Animal models for COVID-19 and tuberculosis.Frontiers in immunology · 2023
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. One Size Fits All? Not inFrontiers in cellular and infection microbiology · 2021
    Review
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Frida ArreyDepartment of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Delia LöweDepartment of Molecular Pharmacology and Cell Biology, Leibniz Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany.
Stefanie KuhlmannDepartment of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Peggy KaiserDepartment of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Pedro Moura-AlvesDepartment of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Gopinath KrishnamoorthyDepartment of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Laura LozzaDepartment of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Jeroen MaertzdorfDepartment of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Tatsiana SkrahinaDepartment of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Alena SkrahinaRepublican Scientific and Practical Centre for Pulmonology and Tuberculosis, Minsk, Belarus.
Martin GengenbacherPublic Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Geraldine NouaillesDivision of Pulmonary Inflammation, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Stefan H E KaufmannDepartment of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany.
Max Planck Institute for Infection Biology · DECharité - Universitätsmedizin Berlin · DELeibniz-Forschungsinstitut für Molekulare Pharmakologie · DERepublican Scientific and Practical Centre of Pulmonology and Tuberculosis · BYRutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human immune system mice are highly valuable for

Indexed as

AnimalsAntitubercular AgentsDisease Models, AnimalDrug Therapy, CombinationFemaleGranulomaHematopoietic Stem Cell TransplantationHumansLungMaleMiceMice, Inbred C57BLMoxifloxacinMycobacterium tuberculosisTuberculosis, PulmonaryAntitubercular AgentsMoxifloxacinantibioticsgranulomahuman immune system micehumanized mouse modelsinfectionlungMycobacterium tuberculosispathology

Identifiers

PMID30766535
PMCPMC6365439
OpenAlexW2914093428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.