Evidence map›Paper›PMID 30766528›Full record

ArticleFrontiers in microbiology2018

Predictable Molecular Adaptation of Coevolving

Stephen Wandro, Andrew Oliver, Tara Gallagher, Claudia Weihe, Whitney England, Jennifer B H Martiny, Katrine Whiteson

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Does Phage Therapy Need a Pan-Phage?Pathogens (Basel, Switzerland) · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Viruses · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Greater Phage Genotypic Diversity Constrains Arms-Race Coevolution.Frontiers in cellular and infection microbiology · 2022
    Article
  17. Article
  18. Lytic bacteriophages facilitate antibiotic sensitization ofAntimicrobial agents and chemotherapy · 2021
    Article
  19. Article
  20. Spontaneous Phage Resistance in Avian PathogenicFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Stephen WandroDepartment of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA, United States.
Andrew OliverDepartment of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA, United States.
Tara GallagherDepartment of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA, United States.
Claudia WeiheDepartment of Ecology and Evolutionary Biology, University of California, Irvine, Irvine, CA, United States.
Whitney EnglandDepartment of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA, United States.
Jennifer B H MartinyDepartment of Ecology and Evolutionary Biology, University of California, Irvine, Irvine, CA, United States.
Katrine WhitesonDepartment of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA, United States.
University of California, Irvine · US

Funding

Virus-host interactions: a multi-scale training programT32AI007319 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI SEMLER, BERT L, SHI, YONGSHENG · 1988 to 2024
$2.4M
NIAID NIH HHS T32 AI007319
6 · The paper itself

Abstract

Bacteriophages are highly abundant in human microbiota where they coevolve with resident bacteria. Phage predation can drive the evolution of bacterial resistance, which can then drive reciprocal evolution in the phage to overcome that resistance. Such coevolutionary dynamics have not been extensively studied in human gut bacteria, and are of particular interest for both understanding and eventually manipulating the human gut microbiome. We performed experimental evolution of an

Indexed as

coevolutionEnterococcusexopolysaccharideexperimental evolutionphage (bacteriophage)phage therapytail fiber

Identifiers

PMID30766528
PMCPMC6365445
OpenAlexW2911419738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.