ReviewAustralian prescriber2019
Nitrofurantoin and fosfomycin for resistant urinary tract infections: old drugs for emerging problems.
Review in Australian prescriber, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05055544 (BeaRberry in the Treatment of Acute UncoMplIcated Cystitis), which is not on this map. Cited by 58 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
BeaRberry in the Treatment of Acute UncoMplIcated Cystitis (BRUMI)- Protocol of a Multicentre, Randomized Double-Blind Clinical Trial
Who cites it
58 citing papers in PubMed, 142 citations in OpenAlex.
- ESKAPE Pathogens in a Hungarian Emergency Department: A 5-Year Retrospective Observational Study of Prevalence and Resistance Patterns Utilizing the AWaRe Framework.Antibiotics (Basel, Switzerland) · 2026Article
- What's in a Name? Etymology and History of Antibacterials and Antifungals.Open forum infectious diseases · 2026Review
- Nitrofurantoin treatment and prophylaxis for recurrent urinary tract infections in women: First-line for a reason.PLoS pathogens · 2026Review
- Nemonoxacin pharmacokinetics/pharmacodynamics againstAntimicrobial agents and chemotherapy · 2026Article
- From Kidneys to Nerves: A Rare Case of a Urinary Tract Infection Triggering Guillain-Barré Syndrome.Cureus · 2026Article
- Urinary tract infections at an Australian sexual health service: bacterial etiologies, antibiotic susceptibilities, and antimicrobial prescribing patterns.Microbiology spectrum · 2026Article
- Therapeutic strategies for multi-resistantJAC-antimicrobial resistance · 2026Review
- Comparative Analysis of Antimicrobial Resistance in Male Uropathogens Before and After the COVID-19 Pandemic: A Single-Center Study from Romania.Medicina (Kaunas, Lithuania) · 2026Article
- Uropathogens' AMR in Male and Female Romanian Population-A Bi-Center Analysis over 1 Year.Medicina (Kaunas, Lithuania) · 2026Article
- Fabrication of nitrofurantoin-loaded chitosan-silver nanoparticles for the treatment of urinary tract infections.Scientific reports · 2026Article
- Antimicrobial resistance patterns in UTIs in male patients with associated kidney stone disease: a descriptive study.Journal of medicine and life · 2026Observational
- Understanding the Burden and Management of Urinary Tract Infections in Women.Diseases (Basel, Switzerland) · 2025Review
- Overcoming the drug resistance barrier: progress in fosfomycin combination therapy against multidrug-resistant pathogens.Frontiers in microbiology · 2025Review
- Unlocking Nitrofurantoin: Understanding Molecular Mechanisms of Action and Resistance in Enterobacterales.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2025Review
- Associations between neighbourhood-level median household income and outpatients' risk of antibiotic non-susceptible uropathogens in a major urban centre, USA.JAC-antimicrobial resistance · 2024Article
- Mitigating antimicrobial resistance, an approach to stewardship in canine urinary tract infection.Veterinary research communications · 2024Article
- The Prevalence of Multidrug-ResistantIndian journal of microbiology · 2024Article
- Regional variations in antimicrobial susceptibility of community-acquired uropathogenicIJID regions · 2024Article
- A Five-Year Analysis of Antibiotic Resistance Trends among Bacteria Identified in Positive Urine Samples in a Tertiary Care Hospital from Bucharest, Romania.Antibiotics (Basel, Switzerland) · 2024Article
- Repurposing antibiotic resistance surveillance data to support treatment of recurrent infections in a remote setting.Scientific reports · 2024Article
Corrections and comments
- Commented on by
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
UNCOMPLICATED URINARY TRACT INFECTION IS ONE OF THE MOST COMMON INDICATIONS FOR ANTIBIOTIC USE IN THE COMMUNITY HOWEVER THE GRAM-NEGATIVE ORGANISMS THAT CAN CAUSE THE INFECTION ARE BECOMING MORE RESISTANT TO ANTIBIOTICS: MANY MULTIDRUG RESISTANT ORGANISMS RETAIN SUSCEPTIBILITY TO TWO OLD ANTIBIOTICS NITROFURANTOIN AND FOSFOMYCIN ADVANTAGES OVER NEWER DRUGS INCLUDE THEIR HIGH URINARY CONCENTRATIONS AND MINIMAL TOXICITY: FOSFOMYCIN IS A POTENTIAL TREATMENT OPTION FOR PATIENTS WITH UNCOMPLICATED URINARY TRACT INFECTION DUE TO RESISTANT ORGANISMS NITROFURANTOIN MAY BE MORE EFFECTIVE AND CAN BE USED FOR URINARY INFECTIONS IN PREGNANT WOMEN:
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.