Evidence map›Paper›PMID 30765878›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2019

Sex-specific association between soluble corin and metabolic syndrome in Chinese adults.

Hongmei Li, Qiu Zhang, Yan He, Jijun Shi, Weidong Hu, Hao Peng

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In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Hongmei Li *Department of Epidemiology, School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Medical College of Soochow University, Suzhou, China.
Qiu Zhang *Center for Disease Prevention and Control of Gusu District, Suzhou, China.
Yan HeDepartment of Epidemiology, School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Medical College of Soochow University, Suzhou, China.
Jijun ShiDepartment of Neurology, Second Affiliated Hospital of Soochow University, Suzhou, China.
Weidong HuDepartment of Neurology, Second Affiliated Hospital of Soochow University, Suzhou, China.
Hao PengDepartment of Epidemiology, School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Medical College of Soochow University, Suzhou, China. penghao@suda.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Soluble corin has been associated with cardiovascular disease and its risk factors, but whether it is associated with metabolic syndrome (MetS), a cluster of cardiometabolic disorders, remains unclear. We aimed to examine the association between soluble corin and MetS in Chinese men and women. We examined serum soluble corin using immunoassays in 962 men (mean age, 53 years) and 1536 women (mean age, 54 years) free of cardiovascular disease. Logistic regression was applied to examine the association between soluble corin and MetS in men and women. The results showed that participants in the 3rd and 4th quartiles of serum soluble corin had 1.99 (95% CI: 1.32-3.00) and 3.84 (95% CI: 2.54-5.83) times the risk of having MetS for men and 1.48 (95% CI: 1.06-2.06) and 1.53 (95% CI: 1.10-2.12) times the risk of having MetS for women compared to those in the lowest quartile. The magnitude of the association between serum soluble corin and MetS was significantly stronger for men than for women (P < 0.001). These results indicated that soluble corin was significantly associated with MetS, and this association was stronger for men than for women. Corin may contribute to cardiometabolic risks differently between men and women and thereby accounting, at least partly, for the sex difference in cardiovascular risk.

Indexed as

AdultAgedAsian PeopleChinaCross-Sectional StudiesFemaleHumansMaleMetabolic SyndromeMiddle AgedRisk FactorsSerine EndopeptidasesSex FactorsCORIN protein, humanSerine EndopeptidasesCardiometabolic risk factorsCross-sectional studyMetabolic syndromeSoluble corin

Identifiers

PMID30765878

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.