ArticleNature communications2019
Subcortical electrophysiological activity is detectable with high-density EEG source imaging.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers, 2 of them syntheses that pooled it.
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Who cites it
144 citing papers in PubMed, 2 syntheses or guidelines pooled it, 287 citations in OpenAlex.
- Pooled it
- Combined Use of EMG and EEG Techniques for Neuromotor Assessment in Rehabilitative Applications: A Systematic Review.Sensors (Basel, Switzerland) · 2021Pooled it
- Subgenual cingulate connectivity and hippocampal activation are related to MST therapeutic and adverse effects.Translational psychiatry · 2020Trial
- Motion Neural Monitoring Based on Flexible Materials: From Signal Acquisition to Training Enhancement.ACS omega · 2026Review
- Assessing Strengths and Limitations of Magnetoencephalography Source Imaging With Intracerebral EEG.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Altered Processing of Auditory Distractions Under Competing Inputs in Children With Attention-Deficit/Hyperactivity Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2026Article
- Neurophysiological connectomic signatures of consciousness during propofol-induced general anesthesia.Cell reports. Medicine · 2026Article
- Inferring neural sources from electroencephalography: foundations and frontiers.Journal of neural engineering · 2026Review
- Article
- Personalized, home-based transcranial alternating current stimulation for memory improvement in mild cognitive impairment: randomized, sham-controlled clinical trial protocol.Frontiers in aging neuroscience · 2026Article
- Human brain imaging with high-density electroencephalography: Techniques and applications.The Journal of physiology · 2026Review
- Mapping epileptogenic brain using a unified spatial-temporal-spectral source imaging framework.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- EEG oscillations and related brain generators of phonation phases in long utterances.Scientific reports · 2025Article
- Harnessing electroencephalography connectomes for cognitive and clinical neuroscience.Nature biomedical engineering · 2025Review
- The Awakening Brain is Characterized by a Widespread and Spatiotemporally Heterogeneous Increase in High Frequencies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Mapping Brain-Wide Neural Activity of Murine Attentional Processing in the Five-Choice Serial Reaction Time Task.Neuroscience bulletin · 2025Article
- TMNRED, A Chinese Language EEG Dataset for Fuzzy Semantic Target Identification in Natural Reading Environments.Scientific data · 2025Article
- Self-related thought alterations associated with intrinsic brain dysfunction in mild cognitive impairment.Scientific reports · 2025Article
- Deep learning-based classification of dementia using image representation of subcortical signals.BMC medical informatics and decision making · 2025Article
- Relationship between regional relative theta power and amyloid deposition in mild cognitive impairment: an exploratory study.Frontiers in neuroscience · 2025Article
84 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Subcortical neuronal activity is highly relevant for mediating communication in large-scale brain networks. While electroencephalographic (EEG) recordings provide appropriate temporal resolution and coverage to study whole brain dynamics, the feasibility to detect subcortical signals is a matter of debate. Here, we investigate if scalp EEG can detect and correctly localize signals recorded with intracranial electrodes placed in the centromedial thalamus, and in the nucleus accumbens. Externalization of deep brain stimulation (DBS) electrodes, placed in these regions, provides the unique opportunity to record subcortical activity simultaneously with high-density (256 channel) scalp EEG. In three patients during rest with eyes closed, we found significant correlation between alpha envelopes derived from intracranial and EEG source reconstructed signals. Highest correlation was found for source signals in close proximity to the actual recording sites, given by the DBS electrode locations. Therefore, we present direct evidence that scalp EEG indeed can sense subcortical signals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.