Evidence map›Paper›PMID 30765600›Full record

ArticleCancer research2019

Cytochrome

Rahul Kumar, Tariq A Bhat, Elise M Walsh, Ajay K Chaudhary, Jordan O'Malley, Johng S Rhim, Jianmin Wang, Carl D Morrison, Kristopher Attwood, Wiam Bshara and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  5. Targeting apoptotic pathways for cancer therapy.The Journal of clinical investigation · 2024
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  16. An N-ethyl-N-Nitrosourea Mutagenesis Screen in Mice Reveals a Mutation inAnimals : an open access journal from MDPI · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Rahul KumarDepartment of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Tariq A BhatDepartment of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York.ORCID 0000-0003-0738-8776
Elise M WalshDepartment of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York.ORCID 0000-0002-2371-102X
Ajay K ChaudharyDepartment of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Jordan O'MalleyDepartment of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Johng S RhimCenter for Prostate Disease Research, Department of Surgery, Uniformed Services University of Health Sciences, Bethesda, Maryland.
Jianmin WangDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Carl D MorrisonDepartment of Pathology, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Kristopher AttwoodDepartment of Biostatistics, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Wiam BsharaPathology Resource Network, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
James L MohlerDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Neelu YadavDepartment of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Dhyan ChandraDepartment of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York. dhyan.chandra@roswellpark.org.ORCID 0000-0001-7272-9384
Roswell Park Comprehensive Cancer Center · USUniformed Services University of the Health Sciences · US

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Dean G. Tang · 1985 to 2026
$116.6M
Immuno-Oncology Translation Network: Data Management and Resource-Sharing Center at RPCIU24CA232979 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI HUTSON, ALAN DAVID, LIU, SONG · 2018 to 2024
$8.9M
Hsp60 regulation of apoptosis in prostate cancerR01CA160685 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI CHANDRA, DHYAN · 2013 to 2018
$1.1M
NCI NIH HHS P30 CA016056NCI NIH HHS R01 CA160685NCI NIH HHS U24 CA232979
6 · The paper itself

Abstract

Although African-American (AA) patients with prostate cancer tend to develop greater therapeutic resistance and faster prostate cancer recurrence compared with Caucasian-American (CA) men, the molecular mechanisms of this racial prostate cancer disparity remain undefined. In this study, we provide the first comprehensive evidence that cytochrome

Indexed as

Black or African AmericanAnimalsApoptosomesCell Line, TumorCytochromes cHumansMaleMiceMice, SCIDMitochondriaMitochondrial MembranesNF-kappa BNuclear Respiratory Factor 1Oxidative PhosphorylationProstatic NeoplasmsProto-Oncogene Proteins c-mycApoptosomesCytochromes cMYC protein, humanNF-kappa BNRF1 protein, humanNuclear Respiratory Factor 1Proto-Oncogene Proteins c-myc

Identifiers

PMID30765600
PMCPMC6445777
OpenAlexW2913106298

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.