Evidence map›Paper›PMID 30765525›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Fate mapping reveals the age structure of the peripheral T cell compartment.

Arnold Reynaldi, Norah L Smith, Timothy E Schlub, Cybelle Tabilas, Vanessa Venturi, Brian D Rudd, Miles P Davenport

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Modeling T Cell Fate.Annual review of immunology · 2023
    Review
  11. Article
  12. Early microbial exposure shapes adult immunity by altering CD8+ T cell development.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Arnold ReynaldiKirby Institute for Infection and Immunity, University of New South Wales, Sydney, NSW 2052, Australia.
Norah L SmithDepartment of Microbiology and Immunology, Cornell University, Ithaca, NY 14853.
Timothy E SchlubSydney School of Public Health, Sydney University, Sydney, NSW 2006, Australia.
Cybelle TabilasDepartment of Microbiology and Immunology, Cornell University, Ithaca, NY 14853.ORCID 0000-0001-5846-7269
Vanessa VenturiKirby Institute for Infection and Immunity, University of New South Wales, Sydney, NSW 2052, Australia.
Brian D RuddDepartment of Microbiology and Immunology, Cornell University, Ithaca, NY 14853; bdr54@cornell.edu m.davenport@unsw.edu.au.
Miles P DavenportKirby Institute for Infection and Immunity, University of New South Wales, Sydney, NSW 2052, Australia; bdr54@cornell.edu m.davenport@unsw.edu.au.

Funding

The developmental layers in the CD8+ T cell response to chronic infectionR01AI110613 · NIAID · CORNELL UNIVERSITY · PI GRIMSON, ANDREW W, RUDD, BRIAN DAVID · 2014 to 2022
$4.1M
Mechanisms Limiting Neonatal ImmunityR01AI105265 · NIAID · CORNELL UNIVERSITY · PI RUDD, BRIAN DAVID · 2014 to 2023
$4.0M
Immuno-Engineering: Integrated Engineering and Immunology TrainingT32EB023860 · NIBIB · CORNELL UNIVERSITY · PI AUGUST, AVERY, PUTNAM, DAVID A · 2018 to 2022
$933k
NIAID NIH HHS R01 AI105265NIAID NIH HHS R01 AI110613NIBIB NIH HHS T32 EB023860
6 · The paper itself

Abstract

Accumulating evidence indicates that the immune system does not develop in a linear fashion, but rather as distinct developmental layers formed from sequential waves of hematopoietic stem cells, each giving rise to unique populations of immune cells at different stages of development. Although recent studies have indicated that conventional CD8

Indexed as

Models, ImmunologicalAgingAnimalsCD8-Positive T-LymphocytesMiceMice, TransgenicCD8+ T cellsimmunologymathematical modelingontogenyT cell homeostasis

Identifiers

PMID30765525
PMCPMC6410819

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.