Evidence map›Paper›PMID 30765521›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Six6 and Six7 coordinately regulate expression of middle-wavelength opsins in zebrafish.

Yohey Ogawa, Tomoya Shiraki, Yoshimasa Asano, Akira Muto, Koichi Kawakami, Yutaka Suzuki, Daisuke Kojima, Yoshitaka Fukada

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 48 citations in OpenAlex.

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  8. Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
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  11. Knockout ofInternational journal of molecular sciences · 2023
    Article
  12. An Overview towards Zebrafish Larvae as a Model for Ocular Diseases.International journal of molecular sciences · 2023
    Review
  13. Article
  14. Article
  15. Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Enhancer transcription identifiesDevelopment (Cambridge, England) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yohey OgawaDepartment of Biological Sciences, School of Science, The University of Tokyo, 113-0033 Tokyo, Japan.
Tomoya ShirakiDepartment of Biological Sciences, School of Science, The University of Tokyo, 113-0033 Tokyo, Japan.
Yoshimasa AsanoDepartment of Biological Sciences, School of Science, The University of Tokyo, 113-0033 Tokyo, Japan.
Akira MutoLaboratory of Molecular and Developmental Biology, National Institute of Genetics, Mishima, 411-8540 Shizuoka, Japan.
Koichi KawakamiLaboratory of Molecular and Developmental Biology, National Institute of Genetics, Mishima, 411-8540 Shizuoka, Japan.
Yutaka SuzukiGraduate School of Frontier Sciences, The University of Tokyo, Kashiwa, 277-0882 Chiba, Japan.
Daisuke KojimaDepartment of Biological Sciences, School of Science, The University of Tokyo, 113-0033 Tokyo, Japan; sdkojima@mail.ecc.u-tokyo.ac.jp sfukada@mail.ecc.u-tokyo.ac.jp.ORCID 0000-0003-2658-780X
Yoshitaka FukadaDepartment of Biological Sciences, School of Science, The University of Tokyo, 113-0033 Tokyo, Japan; sdkojima@mail.ecc.u-tokyo.ac.jp sfukada@mail.ecc.u-tokyo.ac.jp.
The University of Tokyo · JPNational Institute of Genetics · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Color discrimination in the vertebrate retina is mediated by a combination of spectrally distinct cone photoreceptors, each expressing one of multiple cone opsins. The opsin genes diverged early in vertebrate evolution into four classes maximally sensitive to varying wavelengths of light: UV (SWS1), blue (SWS2), green (RH2), and red (LWS) opsins. Although the tetrachromatic cone system is retained in most nonmammalian vertebrate lineages, the transcriptional mechanism underlying gene expression of the cone opsins remains elusive, particularly for SWS2 and RH2 opsins, both of which have been lost in the mammalian lineage. In zebrafish, which have all four cone subtypes,

Indexed as

AnimalsColorColor VisionGene Expression RegulationHomeodomain ProteinsOpsinsRod OpsinsZebrafishZebrafish ProteinsHomeodomain Proteinsmiddle-wavelength opsinOpsinsrh2 protein, zebrafishRod Opsinssix6 protein, zebrafishSix7 protein, zebrafishsws2 protein, zebrafishZebrafish Proteinscolor visioncone opsinphotoreceptor developmenttranscription factorzebrafish retina

Identifiers

PMID30765521
PMCPMC6410792
OpenAlexW2911899062

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.