Evidence map›Paper›PMID 30765477›Full record

ArticleHaematologica2019

SDF1α-induced chemotaxis of JAK2-V617F-positive cells is dependent on Bruton tyrosine kinase and its downstream targets PI3K/AKT, PLCγ1 and RhoA.

Subbaiah Chary Nimmagadda, Stephanie Frey, Peter Müller, Denise Wolleschak, Sönke Weinert, Ulrich Keller, Bärbel Edelmann, Thomas Fischer

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Subbaiah Chary NimmagaddaDepartment of Hematology and Oncology, Medical Center, Otto-von-Guericke University, Magdeburg.
Stephanie FreyDepartment of Hematology and Oncology, Medical Center, Otto-von-Guericke University, Magdeburg.
Peter MüllerDepartment of Hematology and Oncology, Medical Center, Otto-von-Guericke University, Magdeburg.
Denise WolleschakDepartment of Hematology and Oncology, Medical Center, Otto-von-Guericke University, Magdeburg.
Sönke WeinertDepartment of Cardiology and Angiology, Medical Center, Otto-von-Guericke University, Magdeburg.
Ulrich KellerMedical Clinic and Polyclinic III, Klinikum rechts der Isar, Technical University Munich.
Bärbel EdelmannDepartment of Hematology and Oncology, Medical Center, Otto-von-Guericke University, Magdeburg.
Thomas FischerDepartment of Hematology and Oncology, Medical Center, Otto-von-Guericke University, Magdeburg thomas.fischer@med.ovgu.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ChemotaxisGene Expression RegulationMutationAgammaglobulinaemia Tyrosine KinaseCell MovementCells, CulturedChemokine CXCL12HumansJanus Kinase 2Myeloid Progenitor CellsPhosphatidylinositol 3-KinasesPhospholipase C gammaProto-Oncogene Proteins c-aktrhoA GTP-Binding ProteinAgammaglobulinaemia Tyrosine KinaseBTK protein, humanChemokine CXCL12CXCL12 protein, humanJAK2 protein, humanJanus Kinase 2Phosphatidylinositol 3-KinasesPhospholipase C gammaProto-Oncogene Proteins c-aktrhoA GTP-Binding ProteinRHOA protein, human

Identifiers

PMID30765477
PMCPMC6601073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.