Evidence map›Paper›PMID 30765472›Full record

ArticleHaematologica2019

Venetoclax penetrates in cerebrospinal fluid and may be effective in chronic lymphocytic leukemia with central nervous system involvement.

Gianluigi Reda, Ramona Cassin, Gabriela Dovrtelova, Cristina Matteo, Juri Giannotta, Maurizio D'Incalci, Agostino Cortelezzi, Massimo Zucchetti

Abstract readCase ReportsLetter
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  17. Gene Mutations and Targeted Therapies of Myeloid Sarcoma.Current treatment options in oncology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gianluigi RedaHematology Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico of Milan, Italy gianluigi.reda@policlinico.mi.it.
Ramona CassinHematology Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico of Milan, Italy.
Gabriela DovrtelovaDepartment of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Italy.
Cristina MatteoDepartment of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Italy.
Juri GiannottaHematology Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico of Milan, Italy.
Maurizio D'IncalciDepartment of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Italy.
Agostino CortelezziHematology Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico of Milan, Italy.
Massimo ZucchettiDepartment of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsBridged Bicyclo Compounds, HeterocyclicCentral Nervous System NeoplasmsHumansLeukemia, Lymphocytic, Chronic, B-CellMiddle AgedNeoplasm Recurrence, LocalPrognosisSulfonamidesTissue DistributionAntineoplastic AgentsBridged Bicyclo Compounds, HeterocyclicSulfonamidesvenetoclax

Identifiers

PMID30765472
PMCPMC6518888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.