Evidence map›Paper›PMID 30765370›Full record

ArticleCanadian family physician Medecin de famille canadien2019

Multimorbidity predicts functional decline in community-dwelling older adults: Prospective cohort study.

Philip D St John, Suzanne L Tyas, Verena Menec, Robert Tate, Lauren Griffith

Abstract read
In one paragraph

Article in Canadian family physician Medecin de famille canadien, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Relationship between Multimorbidity and Disability in Elderly Patients with Coexisting Frailty Syndrome.International journal of environmental research and public health · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Philip D St JohnGeriatrician in Winnipeg and Associate Professor at the University of Manitoba. pstjohn@hsc.mb.ca.
Suzanne L TyasEpidemiologist and Associate Professor at the University of Waterloo in Ontario.
Verena MenecProfessor in the Department of Community Health Sciences at the University of Manitoba.
Robert TateProfessor in the Department of Community Health Sciences at the University of Manitoba.
Lauren GriffithAssociate Professor in the Department of Clinical Epidemiology and Biostatistics at McMaster University in Hamilton, Ont.
Manitoba Health · CAMcMaster University · CAUniversity of Manitoba · CAUniversity of Waterloo · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine if multimorbidity is associated with functional status, and to assess if multimorbidity predicts declining functional status over a 5-year time frame, after accounting for baseline functional status and other potential confounding factors.

designAnalysis of an existing population-based cohort study.

settingManitoba.

participantsCommunity-dwelling adults aged 65 and older.

main outcome measuresAge, sex, education, and the Mini-Mental State Examination (MMSE) and Center for Epidemiological Studies Depression Scale (CES-D) scores were recorded for each patient. Multimorbidity was measured using a simple tally of self-reported diseases. Function was measured using the Older Americans Resources and Services scale in 1991 to 1992 and again 5 years later. Good or excellent level of function was compared with level of disability (mild or moderate or higher). Cross-sectional and prospective analyses were conducted.

resultsIn a cross-sectional analysis, multimorbidity predicted disability. The unadjusted odds ratio (OR) (95% CI) for disability was 1.45 (1.39 to 1.52) for each additional chronic illness. In models adjusting for age, sex, education, and MMSE and CES-D scores, the adjusted OR (95% CI) was 1.35 (1.29 to 1.42) for each additional chronic illness. Multimorbidity also predicted disability 5 years later. The unadjusted OR (95% CI) was 1.31 (1.24 to 1.38). In models adjusting for age, sex, education, and MMSE and CES-D scores in addition to baseline functional status, the adjusted OR (95% CI) was 1.15 (1.09 to 1.24).

conclusionMultimorbidity predicts disability in cross-sectional and prospective analyses.

Indexed as

Independent LivingMultimorbidityAgedAged, 80 and overChronic DiseaseCross-Sectional StudiesDisability EvaluationFemaleHumansMaleManitobaPersons with DisabilitiesSocioeconomic Factors

Identifiers

PMID30765370
PMCPMC6515497
OpenAlexW2921020736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.