ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2019
Clinical and cortical decline in the aphasic variant of Alzheimer's disease.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 19 citations in OpenAlex.
- Efficacy of Communication Bridge-2 for primary progressive aphasia: A randomized controlled trial of communication intervention.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Trial
- Communication Bridge-2 randomized controlled trial: Recruitment and baseline features.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Trial
- Protocol for a multisite study on the efficacy of transcranial direct current stimulation as an adjuvant to naming and spelling therapy in the treatment of oral and written naming in individuals with primary progressive aphasia.Frontiers in human neuroscience · 2025Article
- Atypical Presentations of Alzheimer Disease.Continuum (Minneapolis, Minn.) · 2024Review
- Association of Regional Cortical Network Atrophy With Progression to Dementia in Patients With Primary Progressive Aphasia.Neurology · 2023Article
- Understanding the multidimensional cognitive deficits of logopenic variant primary progressive aphasia.Brain : a journal of neurology · 2022Review
- Focal amyloid and asymmetric tau in an imaging-to-autopsy case of clinical primary progressive aphasia with Alzheimer disease neuropathology.Acta neuropathologica communications · 2022Article
- Neuropathological fingerprints of survival, atrophy and language in primary progressive aphasia.Brain : a journal of neurology · 2022Article
- The Reliability of Telepractice Administration of the Western Aphasia Battery-Revised in Persons With Primary Progressive Aphasia.American journal of speech-language pathology · 2022Article
- Temporal Cortical Thickness and Cognitive Associations among Typical and Atypical Phenotypes of Alzheimer's Disease.Journal of Alzheimer's disease reports · 2022Article
- Relationships among tau burden, atrophy, age, and naming in the aphasic variant of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021Article
- Functional decline in the aphasic variant of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021Article
- Article
- Accumulation of neurofibrillary tangles and activated microglia is associated with lower neuron densities in the aphasic variant of Alzheimer's disease.Brain pathology (Zurich, Switzerland) · 2021Article
- Article
- Longitudinal neuroimaging biomarkers differ across Alzheimer's disease phenotypes.Brain : a journal of neurology · 2020Article
- Anatomical evidence of an indirect pathway for word repetition.Neurology · 2020Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
introductionPrimary progressive aphasia (PPA) displays variable progression trajectories that require further elucidation.
methodsLongitudinal quantitation of atrophy and language over 12 months was completed for PPA patients with and without positive amyloid PET (PPA
resultsOver 12 months, both PPA groups showed significantly greater cortical atrophy rates in the left versus right hemisphere, with a more widespread pattern in PPA DISCUSSION: Preferential language network neurodegeneration is present in PPA irrespective of amyloid status. Clinical and anatomical progression appears to differ for PPA due to Alzheimer's disease versus non-Alzheimer's disease neuropathology, a distinction that may help to inform prognosis and the design of intervention trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.