Evidence map›Paper›PMID 30765173›Full record

ArticleVaccine2019

Reduction of hospitalizations with diarrhea among children aged 0-5 years in Nouakchott, Mauritania, following the introduction of rotavirus vaccine.

Mohamed-Lemine Cheikh-Brahim Ahmed, Jorg Heukelbach, Abdellahi Weddih, Abdelkarim Filali-Maltouf, Mariem Sidatt, Khattry Makhalla, Sid'Ahmed Dahdi, Aly Cheybany Cheikh Ahmed, Mohamed Val El-Mami, Jacqueline E Tate and 2 more

Abstract read
In one paragraph

Article in Vaccine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mohamed-Lemine Cheikh-Brahim AhmedLaboratory of Microbiology and Molecular Biology, Department of Biology, University Mohammed V, Rabat, Morocco; Unity of Epidemiology and Diversity of Microorganisms, Department of Biology, Faculty of Sciences and Technology, University of Nouakchott El-Asriya, Nouakchott, Mauritania; Department of Epidemiology of Gastroenteritis, CDC Atlanta, USA. Electronic address: lemine1987@hotmail.fr.
Jorg HeukelbachDepartment of Community Health, School of Medicine, Federal University of Ceará, Fortaleza, CE 60430-140, Brazil; College of Public Health, Medical and Veterinary Sciences, Division of Tropical Health and Medicine, James Cook University, Townville, Queensland, Australia.
Abdellahi WeddihDepartment of Pediatric, Faculty of Medicine, University of Nouakchott El-Asriya, Nouakchott, Mauritania; Department of Pediatric, Ministry of Health, Nouakchott, Mauritania.
Abdelkarim Filali-MaltoufLaboratory of Microbiology and Molecular Biology, Department of Biology, University Mohammed V, Rabat, Morocco.
Mariem SidattDepartment of Pediatric, Faculty of Medicine, University of Nouakchott El-Asriya, Nouakchott, Mauritania; Department of Pediatric, Ministry of Health, Nouakchott, Mauritania.
Khattry MakhallaDepartment of Pediatric, Ministry of Health, Nouakchott, Mauritania.
Sid'Ahmed DahdiDepartment of Public Health, Faculty of Medicine, University of Nouakchott El-Asriya, Nouakchott, Mauritania.
Aly Cheybany Cheikh AhmedDepartment of Mother and Child Health, Ministry of Health, Nouakchott, Mauritania.
Mohamed Val El-MamiUnity of Epidemiology and Diversity of Microorganisms, Department of Biology, Faculty of Sciences and Technology, University of Nouakchott El-Asriya, Nouakchott, Mauritania.
Jacqueline E TateDepartment of Epidemiology of Gastroenteritis, CDC Atlanta, USA.
Umesh D ParasharDepartment of Epidemiology of Gastroenteritis, CDC Atlanta, USA.
Mohammed BenhafidUnity of Gastroenteritis, Department of Virology, National Institute of Hygiene, Rabat, Morocco.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

introductionRotavirus vaccine was introduced in Mauritania in December 2014. We investigated hospitalizations with diarrhea during pre and post-vaccination periods among children aged 0-5 years in Nouakchott, the capital of Mauritania.

methodsWe conducted a retrospective review of hospital admission registries from November 1st 2012 through October 31th 2017 at all referral hospitals in Nouakchott. We described admissions of children aged 0-5 years by diagnosis, data of admission, age and sex, and compared the proportion of all childhood hospitalizations with diarrhea before and after rotavirus vaccine introduction.

resultsIn total, 6552 (19%) of all 34,329 hospitalizations in 0-5 year-olds had diarrhea. Of these, 3523/16,952 (20.7%) were recorded during the pre-vaccine period, 1373/6897 (19.9%) during the transition period (November 2014-October 2015), and 1656/10,480 (15.8%) during the post-vaccination period. The proportion of all childhood hospitalizations with diarrhea during the pre-vaccine period was 22.6% among males and 18.7% among females. Approximately one third (32.3%) of hospitalizations with diarrhea occurred in children aged 6-11 months. During the post-vaccination period, the proportion of hospitalizations with diarrhea declined by 24%, and the highest reduction (74%) was observed in children aged 2 to 5 years (P < 0.001).

conclusionsThe proportion of childhood hospitalizations with diarrhea in Nouakchott was reduced by about one fourth after introduction of rotavirus vaccination in Mauritania, indicating a major impact for public health for children in the capital city.

Indexed as

Immunization ProgramsChild, PreschoolDiarrheaFecesFemaleGastroenteritisHospitalizationHumansInfantInfant, NewbornMaleMauritaniaRegistriesRetrospective StudiesRotavirus InfectionsRotavirus VaccinesRotavirus VaccinesDiarrheaMauritaniaNouakchottRotavirusVaccine

Identifiers

PMID30765173
PMCPMC11726317

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.