Evidence map›Paper›PMID 30765118›Full record

ArticleThe International journal on drug policy2019

Comparing Canadian and United States opioid agonist therapy policies.

Kelsey C Priest, Lauren Gorfinkel, Jan Klimas, Andrea A Jones, Nadia Fairbairn, Dennis McCarty

Abstract readComparative Study
In one paragraph

Article in The International journal on drug policy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kelsey C PriestOregon Health & Science University (OHSU) and Portland State University School of Public Health, Portland, OR, 97239, USA; MD/PhD Program, School of Medicine, OHSU, Portland, OR, 97239, USA. Electronic address: priest@ohsu.edu.
Lauren GorfinkelBritish Columbia Centre on Substance Use, University of British Columbia (UBC), Vancouver, BC, V6Z 1Y6, Canada; Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, 10032, USA.
Jan KlimasBritish Columbia Centre on Substance Use, University of British Columbia (UBC), Vancouver, BC, V6Z 1Y6, Canada.
Andrea A JonesDepartment of Psychiatry, UBC, Vancouver, BC, V6Z 1Y6, Canada.
Nadia FairbairnBritish Columbia Centre on Substance Use, University of British Columbia (UBC), Vancouver, BC, V6Z 1Y6, Canada; Department of Medicine, UBC, Vancouver, BC, V6Z 1Y6, Canada.
Dennis McCartyOregon Health & Science University (OHSU) and Portland State University School of Public Health, Portland, OR, 97239, USA; Department of Psychiatry, School of Medicine, OHSU, Portland, OR, 97239, USA.

Funding

Western States Node of the National Drug Abuse Treatment Clinical Trials Network (TMS for CUD) UG1DA015815 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Keith N. Humphreys, Philip Todd Korthuis · 2015 to 2026
$24.6M
Mentoring the next generation of addiction clinician scientists while responding to the opioid epidemicR25DA037756 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI FAIRBAIRN, NADIA · 2014 to 2023
$3.6M
Variation in the Use of Opioid Agonist Treatment in HospitalsF30DA044700 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI PRIEST, KELSEY CAROLINE · 2017 to 2020
$186k
NIDA NIH HHS F30 DA044700NIDA NIH HHS R25 DA037756NIDA NIH HHS UG1 DA015815
6 · The paper itself

Abstract

Canada and the United States (U.S.) face an opioid use disorder (OUD) and opioid overdose epidemic. The most effective OUD treatment is opioid agonist therapy (OAT)-buprenorphine (with and without naloxone) and methadone. Although federal approval for OAT occurred decades ago, in both countries, access to and use of OAT is low. Restrictive policies and complex regulations contribute to limited OAT access. Through a non-systematic literature scan and a review of publicly available policy documents, we examined and compared OAT policies and practice at the federal (Canada vs. U.S.) and local levels (British Columbia [B.C.] vs. Oregon). Differences and similarities were noted between federal and local OAT policies, and subsequently OAT access. In Canada, OAT policy control has shifted from federal to provincial authorities. Conversely, in the U.S., federal authorities maintain primary control of OAT regulations. Local OAT health insurance coverage policies were substantively different between B.C. and Oregon. In B.C., five OAT options were available, while in Oregon, only two OAT options were available with administrative limitations. The differences in local OAT access and coverage policies between B.C. and Oregon, may be explained, in part, to the differences in Canadian and U.S. federal OAT policies, specifically, the relaxation of special federal OAT regulatory controls in Canada. The analysis also highlights the complicating contributions, and likely policy solutions, that exist within other drug policy sub-domains (e.g., the prescription regime, and drug control regime) and broader policy domains (e.g., constitutional rights). U.S. policymakers and health officials could consider adopting Canada's regulatory policy approach to expand OAT access to mitigate the harms of the ongoing opioid overdose epidemic.

Indexed as

BuprenorphineCanadaDrug OverdoseHealth PolicyHumansInsurance CoverageMethadoneNaloxoneOpiate Substitution TreatmentOpioid EpidemicOpioid-Related DisordersUnited StatesBuprenorphineMethadoneNaloxoneBuprenorphinebuprenorphine/naloxoneDrug policyMethadoneOpioid agonist therapyOpioid use disorder

Identifiers

PMID30765118
PMCPMC6689455

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.