ArticleCancer imaging : the official publication of the International Cancer Imaging Society2019
Comparative analysis of the value of diffusion kurtosis imaging and diffusion-weighted imaging in evaluating the histological features of endometrial cancer.
Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed.
- Diffusion kurtosis imaging in predicting pathological grade of intrahepatic cholangiocarcinoma: a preliminary study.Abdominal radiology (New York) · 2026Article
- Non-Gaussian diffusion MRI models for preoperative assessment of microvascular invasion in hepatocellular carcinoma.Abdominal radiology (New York) · 2026Article
- Preoperative risk assessment of endometrial cancer using histogram analysis of weighted and quantitative MRI images.Abdominal radiology (New York) · 2026Article
- Evaluate lymphovascular space invasion in endometrial cancer using diffusion-weighted imaging-based habitat imaging.Scientific reports · 2025Article
- Integrated PET-IVIM-DKI MRI for predicting lymphovascular invasion in NSCLC.Insights into imaging · 2025Article
- Risk Stratification Prediction of Endometrial Cancer Using Microstructural Mapping Based on Time-Dependent Diffusion MRI.Cancer science · 2025Article
- Preoperative prediction of aggressive endometrial cancer using multiparametric MRI-based deep transfer learning models.Frontiers in oncology · 2025Article
- A comparative study of mono-exponential and advanced diffusion-weighted imaging in differentiating stage IA endometrial carcinoma from benign endometrial lesions.Journal of cancer research and clinical oncology · 2024Article
- Diffusion kurtosis imaging with multiple quantitative parameters for predicting microsatellite instability status of endometrial carcinoma.Abdominal radiology (New York) · 2023Article
- Role of T2 mapping of magnetic resonance imaging in the differentiation of endometrial cancer and benign endometrial lesionsDiagnostic and interventional radiology (Ankara, Turkey) · 2023Article
- Current Update on PET/MRI in Gynecological Malignancies-A Review of the Literature.Current oncology (Toronto, Ont.) · 2023Review
- Magnetic resonance spectroscopy associations with clinicopathologic features of estrogen-dependent endometrial cancer.BMC medical imaging · 2022Article
- Diffusion weighted imaging and diffusion kurtosis imaging in abdominal oncological setting: why and when.Infectious agents and cancer · 2022Review
- A comparative analysis of MRI findings in endometrial cancer: differentiation between endometrioid adenocarcinoma, serous carcinoma, and clear cell carcinoma.European radiology · 2022Article
- Article
- Multi-Parameter MR Radiomics Based Model to Predict 5-Year Progression-Free Survival in Endometrial Cancer.Frontiers in oncology · 2022Article
- Evaluation of Amide Proton Transfer-Weighted Imaging for Risk Factors in Stage I Endometrial Cancer: A Comparison With Diffusion-Weighted Imaging and Diffusion Kurtosis Imaging.Frontiers in oncology · 2022Article
- Application of diffusion kurtosis tensor MR imaging in characterization of renal cell carcinomas with different pathological types and grades.Cancer imaging : the official publication of the International Cancer Imaging Society · 2021Article
- Combination Analysis of a Radiomics-Based Predictive Model With Clinical Indicators for the Preoperative Assessment of Histological Grade in Endometrial Carcinoma.Frontiers in oncology · 2021Article
- Application of the amide proton transfer-weighted imaging and diffusion kurtosis imaging in the study of cervical cancer.European radiology · 2020Article
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Abstract
purposeThis study evaluated and compared the performances of diffusion kurtosis imaging (DKI) and diffusion-weighted imaging (DWI) for diagnosing and histologically grading endometrial cancer. MATERIALS AND
methodsIn this retrospective study, DKI and DWI data for 61 patients with endometrial cancer and 30 patients with a normal endometrium were analyzed, and the mean kurtosis (MK), mean diffusion coefficient (MD) and apparent diffusion coefficient (ADC) values for the endometrial cancer tissue and normal endometrial tissue were acquired. The parameters for the normal endometrium group (G0) and the endometrial cancer groups (G1, G2 and G3) were compared and analyzed. The receiver operating characteristic (ROC) curve was used to evaluate each parameter's diagnostic accuracy and threshold. Spearman correlation analysis was used to analyze the correlations between all parameters and histological grades.
resultsThe MK values for the G0, G1, G2 and G3 groups increased gradually, while the MD and ADC values decreased gradually. Except for the differences in the ADC values between G0 and G1, the differences among the groups were statistically significant (P < 0.05). The MK values had the highest diagnostic accuracy in differentiating G0 and (G1 + G2 + G3), G0 and G1, G1 and G2, and G2 and G3 (AUC = 0.93, 0.76, 0.91, 0.91, P < 0.05). MK was maximally correlated with histological grade, followed by MD and ADC (MK > MD > ADC; r = - 0.85, + 0.82, + 0.76, P < 0.01).
conclusionBoth DKI and DWI can be used to evaluate the diagnosis and histological grading of endometrial cancer. Compared with DWI, the DKI model is a more complete mathematical model with more sensitive parameters, which can more effectively evaluate the pathological and physiological characteristics of endometrial cancer.
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