Evidence map›Paper›PMID 30764842›Full record

ArticleHealth and quality of life outcomes2019

Responsiveness and minimal clinically important difference of the Minnesota living with heart failure questionnaire.

M Gonzalez-Saenz de Tejada, A Bilbao, L Ansola, R Quirós, L García-Perez, G Navarro, A Escobar

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Health and quality of life outcomes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  3. Exercise-based cardiac rehabilitation for adults with heart failure.The Cochrane database of systematic reviews · 2024
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  14. Health-related quality of life is an independent predictor of mortality and hospitalisations in transthyretin amyloid cardiomyopathy: a prospective cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M Gonzalez-Saenz de TejadaResearch Unit, Basurto University Hospital, Jado 4th floor, Avda Montevideo 18, 48013, Bilbao, Vizcaya, Spain. marta.gonzalezsaenzdetejada@osakidetza.eus.
A BilbaoResearch Unit, Basurto University Hospital, Jado 4th floor, Avda Montevideo 18, 48013, Bilbao, Vizcaya, Spain.
L AnsolaResearch Unit, Basurto University Hospital, Jado 4th floor, Avda Montevideo 18, 48013, Bilbao, Vizcaya, Spain.
R QuirósRed de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC), Madrid, Spain.
L García-PerezRed de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC), Madrid, Spain.
G NavarroEpidemiology Unit, Hospital Universitari, Parc Taulí 1, 08208, Sabadell, Barcelona, Spain.
A EscobarResearch Unit, Basurto University Hospital, Jado 4th floor, Avda Montevideo 18, 48013, Bilbao, Vizcaya, Spain.

Funding

Department of Health of Basque Government 2008111017Instituto de Salud Carlos III PS09/00865Instituto de Salud Carlos III PS09/01053Instituto de Salud Carlos III PS09/01129Instituto de Salud Carlos III PS09/01770
6 · The paper itself

Abstract

backgroundThe Minnesota Living with Heart Failure Questionnaire (MLHFQ) is one of the most widely used health-related quality of life questionnaires for patients with heart failure (HF). The objective of the present study was to explore the responsiveness of the MLHFQ by estimating the minimal detectable change (MDC) and the minimal clinically important difference (MCID) in Spain.

methodsPatients hospitalized for HF in the participating hospitals completed the MLHFQ at baseline and 6 months, plus anchor questions at 6 months. To study responsiveness, patients were classified as having "improved", remained "the same" or "worsened", using anchor questions. We used the standardized effect size (SES), and standardized response mean (SRM) to measure the magnitude of the changes scores and calculate the MDC and MCID.

resultsOverall, 1211 patients completed the baseline and follow-up questionnaires 6 months after discharge. The mean changes in all MLHFQ domains followed a trend (P < 0.0001) with larger gains in quality of life among patients classified as "improved", smaller gains among those classified as "the same", and losses among those classified as "worsened". The SES and SRM responsiveness parameters in the "improved" group were ≥ 0.80 on nearly all scales. Among patients classified as "worsened", effect sizes were < 0.40, while among patients classified as "the same", the values ranged from 0.24 to 0.52. The MDC ranged from 7.27 to 16.96. The MCID based on patients whose response to the anchor question was "somewhat better", ranged from 3.59 to 19.14 points.

conclusionsAll of these results suggest that all domains of the MLHFQ have a good sensitivity to change in the population studied.

Indexed as

Minimal Clinically Important DifferenceQuality of LifeAdultAgedFemaleHeart FailureHumansMaleMiddle AgedMinnesotaSpainSurveys and QuestionnairesHealth-related quality of lifeHeart failureMinimal clinically important differenceMinnesota living with heart failure questionnairePsychometric propertiesResponsiveness

Identifiers

PMID30764842
PMCPMC6376687

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.