Evidence map›Paper›PMID 30764819›Full record

ArticleBMC medicine2019

A scoping review of health-related stigma outcomes for high-burden diseases in low- and middle-income countries.

Jeremy C Kane, Melissa A Elafros, Sarah M Murray, Ellen M H Mitchell, Jura L Augustinavicius, Sara Causevic, Stefan D Baral

Registry-linked trialAbstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07425925 (Feasibility and Effectiveness of Digital Peer-support-based Anti-HIV Stigma Intervention in Improving Clinical Outcomes Among Adolescents Living With HIV in Ethiopia), which is not on this map. Cited by 172 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
172citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07425925 narecruitingnot on this mapstarted 2025, after this paper: background citation

Feasibility and Effectiveness of Digital Peer-support-based Anti-HIV Stigma Intervention in Improving Clinical Outcomes Among Adolescents Living With HIV in Ethiopia

TypeinterventionalSponsorLund UniversityRan2025 to 2026Enrolled282ConditionsHIV-related Stigma, Psychological Wellbeing, Retention in CareArmsPeer support based digital anti-HIV stigma intervention, A standard in-clinic in-person psychosocial support
3 · Its place in the literature

Who cites it

172 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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112 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeremy C KaneDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, 624 North Broadway, Baltimore, MD, 21205, USA. jkane29@jhu.edu.ORCID 0000-0002-6598-3840
Melissa A ElafrosDepartment of Neurology, Johns Hopkins School of Medicine, Sheikh Zayed Tower, Room 6005, 1800 Orleans Street, Baltimore, MD, 21205, USA.
Sarah M MurrayDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, 624 North Broadway, Baltimore, MD, 21205, USA.
Ellen M H MitchellInternational Institute for Social Studies, Erasmus University, Kortenaerkade 12, 2518 AX, The Hague, Netherlands.
Jura L AugustinaviciusDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, 624 North Broadway, Baltimore, MD, 21205, USA.
Sara CausevicDepartment of Public Health Sciences, Karolinska Institutet, Widerströmska huset, Tomtebodavägen 18A, 171 77, Stockholm, Sweden.
Stefan D BaralDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD, 21205, USA.

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Anna Palmer Durbin · 2012 to 2026
$67.0M
Validation of Stigma Metrics for Marginalized Men R01MH110358 · NIMH · JOHNS HOPKINS UNIVERSITY · PI BARAL, STEFAN DAVID · 2017 to 2021
$3.6M
NIAID NIH HHS P30 AI094189NIMH NIH HHS R01 MH110358
6 · The paper itself

Abstract

backgroundStigma is associated with health conditions that drive disease burden in low- and middle-income countries (LMICs), including HIV, tuberculosis, mental health problems, epilepsy, and substance use disorders. However, the literature discussing the relationship between stigma and health outcomes is largely fragmented within disease-specific siloes, thus limiting the identification of common moderators or mechanisms through which stigma potentiates adverse health outcomes as well as the development of broadly relevant stigma mitigation interventions.

methodsWe conducted a scoping review to provide a critical overview of the breadth of research on stigma for each of the five aforementioned conditions in LMICs, including their methodological strengths and limitations.

resultsAcross the range of diseases and disorders studied, stigma is associated with poor health outcomes, including help- and treatment-seeking behaviors. Common methodological limitations include a lack of prospective studies, non-representative samples resulting in limited generalizability, and a dearth of data on mediators and moderators of the relationship between stigma and health outcomes.

conclusionsImplementing effective stigma mitigation interventions at scale necessitates transdisciplinary longitudinal studies that examine how stigma potentiates the risk for adverse outcomes for high-burden health conditions in community-based samples in LMICs.

Indexed as

Social StigmaDeveloping CountriesEpilepsyHIV InfectionsHumansMaleMental DisordersSubstance-Related DisordersTuberculosisDepressionEpilepsyHIVLow- and middle-income countriesScoping reviewStigmaSubstance useTuberculosis

Identifiers

PMID30764819
PMCPMC6376728

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.