Evidence map›Paper›PMID 30764697›Full record

ArticleJournal of the American Heart Association2019

Complex Role for E-Prostanoid 4 Receptors in Hypertension.

Marcela Herrera, Ting Yang, Matthew A Sparks, Michael W Manning, Beverly H Koller, Thomas M Coffman

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. AdaptiveiScience · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Complex Role for E-Prostanoid 4 Receptors in Hypertension.Journal of the American Heart Association · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Marcela Herrera1 Division of Nephrology Department of Medicine Duke University Durham NC.
Ting Yang1 Division of Nephrology Department of Medicine Duke University Durham NC.
Matthew A Sparks1 Division of Nephrology Department of Medicine Duke University Durham NC.
Michael W Manning2 Department of Anesthesiology Duke University Durham NC.
Beverly H Koller4 Department of Genetics University of North Carolina Chapel Hill NC.
Thomas M Coffman1 Division of Nephrology Department of Medicine Duke University Durham NC.
Duke University · USDurham VA Medical Center · USNational University of Singapore · SGUniversity of North Carolina at Chapel Hill · US

Funding

Paracrine Control of Blood Pressure by Renal Intercalated CellsR01DK105049 · NIDDK · DUKE UNIVERSITY · PI COFFMAN, THOMAS M · 2015 to 2019
$1.8M
Renal Endothelin-1: Control of Sodium Excretion and Blood PressureK99HL109167 · NHLBI · DUKE UNIVERSITY · PI HERRERA, MARIA MARCELA · 2012 to 2013
$177k
BLRD VA IK2 BX002240NHLBI NIH HHS K99 HL109167NIDDK NIH HHS R01 DK105049
6 · The paper itself

Abstract

Background Prostaglandin E

Indexed as

Angiotensin IIAnimalsBlood PressureDinoprostoneDisease Models, AnimalHypertensionInfusions, IntravenousMiceMice, TransgenicReceptors, Prostaglandin E, EP4 SubtypeRestSignal TransductionVasoconstrictor AgentsVasodilationAngiotensin IIDinoprostoneReceptors, Prostaglandin E, EP4 SubtypeVasoconstrictor Agentsangiotensin IIblood pressureE‐prostanoid 4 receptorhypertensionprostaglandin E2reninvascular smooth muscle cells

Identifiers

PMID30764697
PMCPMC6405651
OpenAlexW2912188831

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.