Evidence map›Paper›PMID 30764662›Full record

ReviewJournal of investigative medicine high impact case reports

Primary Esophageal Diffuse Large B-Cell Lymphoma: A Comparative Review of 15 Cases.

Faisal Inayat, Ahmed Munir, Ahsan Wahab, Fariha Younus, Fahad Zafar, Waqas Ullah

Abstract readCase ReportsReview
In one paragraph

Review in Journal of investigative medicine high impact case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Primary Esophageal Lymphoma: A Rare Entity.GE Portuguese journal of gastroenterology · 2022
    Article
  6. Histopathological landscape of rare oesophageal neoplasms.World journal of gastroenterology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Faisal Inayat1 Allama Iqbal Medical College, Lahore, Pakistan.ORCID 0000-0001-7576-7319
Ahmed Munir2 Services Institute of Medical Sciences, Lahore, Pakistan.
Ahsan Wahab3 McLaren Regional Medical Center, Flint, MI, USA.ORCID 0000-0003-3597-1838
Fariha Younus2 Services Institute of Medical Sciences, Lahore, Pakistan.
Fahad Zafar4 King Edward Medical University, Lahore, Pakistan.
Waqas Ullah5 Abington - Jefferson Health, Abington, PA, USA.ORCID 0000-0002-4850-0309

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary esophageal diffuse large B-cell lymphoma (DLBCL) is an extremely rare clinicopathologic entity. We report one case from our clinical experience and undertake a review of the previously published cases. A systematic literature search of the medical databases PubMed and Google Scholar was conducted. A total of 15 cases fulfilled the inclusion criteria. The data on patients' characteristics, epidemiology, clinical features, HIV status, gross appearance of the lesion, esophageal location, treatment, and outcome were collected and analyzed. Primary esophageal DLBCL was more common among males, primarily in the fifth and sixth decades of life. Dysphagia was the most common initial clinical presentation. Tissue biopsy with immunohistochemistry was an indispensable diagnostic modality. The mainstay of treatment was chemotherapy with cyclophosphamide, vincristine, doxorubicin, and prednisone regimen, in addition to anti-CD20 antibody rituximab, with or without radiotherapy. This review serves to outline our current understanding of the epidemiology of and risk factors for primary esophageal DLBCL, the pathophysiology of this disorder, and currently available approaches to diagnosis and management.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsDeglutition DisordersEsophageal NeoplasmsFemaleHumansImmunohistochemistryLymphoma, Large B-Cell, DiffuseMiddle AgedRadiotherapyTreatment Outcomediagnosisdiffuse large B-cell lymphomaincidencemanagementprimary esophageal lymphoma

Identifiers

PMID30764662
PMCPMC6305950

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.