Evidence map›Paper›PMID 30764642›Full record

ArticleBiological research for nursing2019

Associations of Hormonal Biomarkers With Mental Health and Healthy Behaviors Among Mothers of Very-Low-Birthweight Infants.

June Cho, Xiaogang Su, Diane Holditch-Davis

Open access · greenAbstract read
In one paragraph

Article in Biological research for nursing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

June Cho1 School of Nursing, University of Nevada, Las Vegas, NV, USA.
Xiaogang Su2 Department of Mathematical Sciences, University of Texas at El Paso, El Paso, TX, USA.
Diane Holditch-Davis3 School of Nursing, Duke University, Durham, NC, USA.
Duke University · USThe University of Texas at El Paso · USUniversity of Nevada, Las Vegas · US

Funding

Testosterone and Cortisol Levels in Infant Health and DevelopmentR01HD076871 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHO, JUNE I · 2014 to 2016
$959k
NICHD NIH HHS R01 HD076871
6 · The paper itself

Abstract

objectivesTo examine the concurrent use of self-report questionnaires and hormonal biomarkers, specifically levels of testosterone and cortisol, along with demographic variables and corrected age (CA) in the assessment of mental health and healthy behaviors among mothers of very-low-birthweight (VLBW, BW < 1,500 g) infants at five time points over 2 years post birth.

methodData on 40 mothers from a neonatal intensive care unit of a tertiary medical center in the southeast United States were collected from the medical record, standard questionnaires for the mother (depressive symptoms, perceived stress, anxiety, mental health status, parenting stress, and healthy lifestyle behaviors), and biochemical measurement of maternal testosterone and cortisol using enzyme immunoassay at birth, 40 weeks' postmenstrual age, and 6, 12, and 24 months CA.

resultsMaternal self-report of mental health improved from birth to 6 or 12 months then worsened at 24 months. Mixed linear models showed that mothers with higher testosterone levels had more depressive symptoms and smoked more, whereas mothers with higher cortisol levels had healthier behaviors and exercised more. Testosterone levels were negatively correlated with cortisol levels. Marital status, education, and health insurance were the most predictive demographic variables for the levels of hormonal biomarkers, mental health, and healthy behaviors.

conclusionsThe use of self-report and biochemical measurement was effective in assessing maternal mental health and healthy behaviors over 2 years post birth, when mothers of VLBW infants tend to experience more mental health problems and parenting difficulties than mothers of normal-BW full-term infants.

Indexed as

AdultBiomarkersFemaleHealth BehaviorHumansHydrocortisoneInfantInfant, NewbornInfant, Very Low Birth WeightIntensive Care Units, NeonatalMaleMental DisordersMental HealthMothersPregnancySoutheastern United StatesBiomarkersHydrocortisoneTestosteronehormonal biomarkersmaternal healthy behaviorsmaternal mental health

Identifiers

PMID30764642
PMCPMC6700898
OpenAlexW2913326984

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.