ArticleNeuroImage. Clinical2019
Volume alterations of brainstem subregions in migraine with aura.
Article in NeuroImage. Clinical, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Application of machine learning in migraine classification: a call for study design standardization and global collaboration.The journal of headache and pain · 2025Pooled it
- What does a migraine aura look like?-A systematic review.The journal of headache and pain · 2025Pooled it
- Dysphasia and Other Higher Cortical Dysfunctions During the Migraine Aura-a Systematic Review of Literature.Current pain and headache reports · 2020Pooled it
- Triggers, prodrome, aura, and headache interactions in migraine with typical aura: a prospective deep-phenotyping study.The journal of headache and pain · 2026Observational
- Aging pattern of the brainstem based on volumetric measurement and optimized surface shape analysis.Brain imaging and behavior · 2024Article
- Breast cancer brain metastases localization and risk of hydrocephalus: a single institution experience.Journal of neuro-oncology · 2023Article
- Evaluating migraine with typical aura with neuroimaging.Frontiers in human neuroscience · 2023Review
- Patients With Vestibular Migraine are More Likely to Have Occipital Headaches than those With Migraine Without Vestibular Symptoms.Headache · 2020Article
- Regional volume changes of the brain in migraine chronification.Neural regeneration research · 2020Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe brainstem plays a significant role in migraine pathogenesis, but a relationship between volume alterations of brainstem subregions and migraine aura characteristics has not been sufficiently investigated. The aim of this study is to compare the volume of the brainstem, and its subregions, between patients with a migraine with aura (MwA) and healthy controls (HC), and also to correlate characteristics of MwA and the volume of the brainstem subregions.
methodsForty-two MwA and 42 HCs, balanced by sex and age, were selected for this study. Total brainstem volume changes as well as volume changes in the pons, medulla, midbrain and the superior cerebellar peduncles were investigated in MwA relative to HCs. In addition, the relationships between brainstem subregions and aura characteristics (aura duration, the frequency of the aura, occurrence of somatosensory and dysphasic aura, duration of a headache, intensity of headache pain and disease duration) were explored in MwA.
resultsMwA patients had a larger brainstem volume relative to HCs (25,941.35 ± 2559.2 mm
conclusionThe results of this study reveal that a migraine with aura is associated with a larger volume of the brainstem with a particular involvement of the midbrain and pons.
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