Evidence map›Paper›PMID 30763868›Full record

ArticleSleep medicine2019

Insomnia symptoms and short sleep predict anxiety and worry in response to stress exposure: a prospective cohort study of medical interns.

David A Kalmbach, James L Abelson, J Todd Arnedt, Zhuo Zhao, Jessica R Schubert, Srijan Sen

Abstract read
In one paragraph

Article in Sleep medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
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  17. Association between sleep health and rates of self-reported medical errors in intern physicians: an ancillary analysis of the Intern Health Study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

David A KalmbachThomas Roth Sleep Disorders & Research Center, Henry Ford Health System, Novi, MI, USA.
James L AbelsonDepartment of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA.
J Todd ArnedtDepartment of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA.
Zhuo ZhaoDepartment of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA.
Jessica R SchubertDepartment of Behavioral Health, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Srijan SenDepartment of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: srijan@med.umich.edu.
University of Michigan–Ann Arbor · USHenry Ford Health System · USVA Ann Arbor Healthcare System · US

Funding

Mobile Technology to Identify Behavorial Mechanisms Linking Genetic Variation and DepressionR01MH101459 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEN, SRIJAN · 2013 to 2023
$6.4M
Multi-Institutional Training in Genetic/Genomic Approaches to Sleep DisordersT32HL110952 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHERVIN, RONALD D, MIGNOT, EMMANUEL J · 2013 to 2022
$5.0M
NHLBI NIH HHS T32 HL110952NIMH NIH HHS R01 MH101459
6 · The paper itself

Abstract

STUDY

objectivesWhile anxiety rates are alarmingly high in short sleeping insomniacs, the relationship between insomnia and anxiety symptoms has not been extensively studied, especially in comparison to the relationship between insomnia and depressive symptoms. Using residency training as a naturalistic stress exposure, we prospectively assessed the role of sleep disturbance and duration on anxiety-risk in response to stress.

methodsWeb-based survey data from 1336 first-year training physicians (interns) prior to and then quarterly across medical internship. Using mixed effects modeling, we examined how pre-internship sleep disturbance and internship sleep duration predicted symptoms of anxiety, using an established tool for quantifying symptom severity in generalized anxiety disorder (GAD).

resultsPre-internship poor sleepers are at more than twice the odds of having short sleep (≤6 h) during internship as good sleepers (OR = 2.38, 95% CI = 1.61, 3.57). Poor sleepers were also at twice the odds for screening positive for probable GAD diagnosis (OR = 2.08, 95% CI = 1.26, 3.45). Notably, sleep onset insomnia strongly predicted anxiety development under stress (OR = 3.55, 95% CI = 1.49, 8.45). During internship, short sleep associated with concurrent anxiety symptoms (b = -0.26, 95% CI = -0.38, -0.14) and predicted future anxiety symptoms even more strongly (b = -0.39, 95% CI = -0.76, -0.03).

conclusionsPoor sleepers, particularly those with sleep onset insomnia symptoms, are vulnerable to short sleep and GAD anxiety and worry during chronic stress.

Indexed as

AdultAnxietyCohort StudiesFemaleHumansInternship and ResidencyMaleOccupational StressPredictive Value of TestsProspective StudiesSleepSleep Initiation and Maintenance DisordersAnxietyInsomniaPhysiciansResidentsStressWorry

Identifiers

PMID30763868
PMCPMC7045299
OpenAlexW2904061626

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.