Evidence map›Paper›PMID 30763731›Full record

ArticleThe journal of allergy and clinical immunology. In practice

Vitamin D Status Modifies the Response to Indoor Particulate Matter in Obese Urban Children with Asthma.

Sonali Bose, Gregory B Diette, Han Woo, Kirsten Koehler, Karina Romero, Ana M Rule, Barbara Detrick, Emily Brigham, Meredith C McCormack, Nadia N Hansel

Abstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Docosahexaenoic Acid and Its Metabolites Protect against Ozone-induced Pulmonary Inflammation.American journal of respiratory cell and molecular biology · 2025
    Article
  7. Review
  8. The role of antioxidant nutrients in mitigating PMFrontiers in public health · 2025
    Article
  9. Article
  10. Indoor air pollution and airway health.The Journal of allergy and clinical immunology · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. The Role of Vitamins in the Pathogenesis of Asthma.International journal of molecular sciences · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Obesity-related asthma in children and adolescents.The Lancet. Child & adolescent health · 2022
    Review
  20. Asthma interactions between obesity and other risk factors.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Sonali BoseDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Md.
Gregory B DietteDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Md; Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md.
Han WooDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Md.
Kirsten KoehlerEnvironmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md.
Karina RomeroDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Md.
Ana M RuleEnvironmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md.
Barbara DetrickDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, Md.
Emily BrighamDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Md.
Meredith C McCormackDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Md; Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md.
Nadia N HanselDepartment of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Md; Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md. Electronic address: nhansel1@jhmi.edu.

Funding

Oxidative Stress & Inflammation in a Human PM Nasal ChallengeP50ES015903 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI MATSUI, ELIZABETH C. · 2007 to 2011
$12.1M
Institute for Clinical and Translational ResearchKL2TR001077 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$9.2M
The role of obesity in biological responses to particulate matter in miceP50ES018176 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI HANSEL, NADIA N · 2015 to 2019
$4.8M
Project 3: Dissecting the Diet Asthma Relationship in Mice Models of AsthmaP01ES018176 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI BISWAL, SHYAM · 2009 to 2013
$4.2M
Mentoring in Patient-Oriented Research on Asthma and the Indoor EnvironmentK24AI114769 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI MATSUI, ELIZABETH C. · 2015 to 2023
$1.6M
Relationship Between Indoor Ultrafine Particle Exposure and Respiratory Morbidity, Inflammation, and Oxidative Stress in Children with AsthmaK23ES029105 · NIEHS · UNIVERSITY OF BRITISH COLUMBIA · PI BRIGHAM, EMILY · 2019 to 2022
$755k
Vitamin D and Susceptibility to Inhaled Pollutants in Urban Children with AsthmaF32ES019420 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI BOSE, SONALI · 2010 to 2011
$118k
NCATS NIH HHS KL2 TR001077NIAID NIH HHS K24 AI114769NIEHS NIH HHS F32 ES019420NIEHS NIH HHS K23 ES029105NIEHS NIH HHS P01 ES018176NIEHS NIH HHS P50 ES015903NIEHS NIH HHS P50 ES018176
6 · The paper itself

Abstract

backgroundIndoor fine particulate air pollution (PM

objectiveWe aimed to determine if vitamin D modifies the effects of indoor PM

methodsA total of 120 children aged 5 to 12 years with physician-diagnosed asthma were evaluated at baseline and every 3 months for 9 months. Indoor PM

resultsChildren were of mean (standard deviation [SD]) age 9.7 (2.2) years, 36% were obese, and 95% self-reported black race. Mean (SD) PM

conclusionsAmong obese urban children with asthma, low individual 25-OH D enhanced adverse respiratory effects associated with indoor PM

Indexed as

Air PollutantsAir Pollution, IndoorAsthmaChildChild, PreschoolFemaleHumansMaleObesityParticulate MatterUrban PopulationVitamin DVitaminsAir PollutantsParticulate MatterVitamin DVitaminsAsthmaObesityParticulate matterVitamin D

Identifiers

PMID30763731
PMCPMC6792389

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.