ArticlePreventive medicine2019
Prescription opioid misuse among middle-aged and older adults in the United States, 2015-2016.
Article in Preventive medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Hydromorphone for cancer pain.The Cochrane database of systematic reviews · 2021Pooled it
- Medication and Acute Care Use in Young Adults With Opioid Use Subject to Medicaid Prescription Caps.JAMA health forum · 2026Article
- The Economic burden of opioid-related serious adverse events and undertreatment of acute pain in the United States.Frontiers in public health · 2026Review
- Social Determinants of Health Among Individuals Receiving Opioids for Pain Management.The Clinical journal of pain · 2025Article
- Demographic, Social, Behavioral, and Clinical Characteristics Associated with Long-Term Opioid Therapy and Any Opioid Prescription in High-Risk VA Patients.Journal of general internal medicine · 2025Article
- Medicare Beneficiary Receipt of Methadone by Drive Time to Opioid Treatment Programs.JAMA network open · 2025Article
- Individual and prescription level factors associated with overdose in opioid naïve older people.Journal of the American Geriatrics Society · 2025Article
- The Influence of Multiple Modifiable Risk Factors on 30-day Readmissions and 90-day Major Complications After a Total Hip and Knee Arthroplasty: An Analysis of a Large Claims Database.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Social Withdrawal and Prescription Opioid Misuse Among Older Adults in the United States.Innovation in aging · 2025Article
- Sources of nonmedically used prescription psychotherapeutic drugs using real-world data from adolescents and adults assessed for substance use treatment--2014-2022.Research in social & administrative pharmacy : RSAP · 2024Article
- Incidence of opioid misuse by cigarette smoking status in the United States.Addictive behaviors · 2023Article
- Substance use and medical outcomes in those age 50 and older involving cocaine and metamfetamine reported to United States poison centers.Clinical toxicology (Philadelphia, Pa.) · 2023Article
- Impacts of medical and non-medical cannabis on the health of older adults: Findings from a scoping review of the literature.PloS one · 2023Article
- Patterns in Geographic Distribution of Substance Use Disorder Treatment Facilities in the US and Accepted Forms of Payment From 2010 to 2021.JAMA network open · 2022Article
- Discharge locations after hospitalizations involving opioid use disorder among medicare beneficiaries.Addiction science & clinical practice · 2022Article
- Opioids and older adults: Increasing trends in opioid usage in a dental population compared to a National Database (NHANES).Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry · 2022Article
- Sociodemographic and Clinical Predictors of Prescription Opioid Use in a Longitudinal Community-Based Cohort Study of Middle-Aged and Older Adults.Journal of aging and health · 2022Article
- Disparities by Sex and Race and Ethnicity in Death Rates Due to Opioid Overdose Among Adults 55 Years or Older, 1999 to 2019.JAMA network open · 2022Article
- Personal and Social Consequences of Psychotropic Substance Use: A Population-Based Internet Survey.Medicina (Kaunas, Lithuania) · 2022Article
- Opioid-involved prescription drug misuse and poly-prescription drug misuse in U.S. older adults.Aging & mental health · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Adults ≥50 years of age have high rates of prescription opioid use. The purpose of this study is to estimate the prevalence and correlates of prescription opioid misuse among middle-aged and older adults in the United States who use prescription opioids. Data from adults age ≥ 50 from the two most recent cohorts (2015 and 2016) of the National Survey of Drug Use and Health were examined (N = 17,608). Characteristics of past-year prescription opioid misusers, including demographics, substance use, depression, chronic disease, and emergency department (ED) use, were compared to adults who used prescription opioids as prescribed in the past year and non-users. We used multivariable logistic regression to determine correlates of prescription opioid misuse among adults who used prescription opioids. Among the entire sample, 61.4% reported no past-year prescription opioid use, 36.0% reported past-year prescription opioid use without misuse, and 2.5% reported past-year prescription opioid misuse. Among past-year prescription opioid users, 6.6% reported misuse. Past-year misuse was higher among males, adults age 50-64, misusers of prescription sedatives, stimulants, and tranquilizers, users of other substances (i.e., tobacco, marijuana, cocaine), and those with alcohol use disorder. Past-year misuse was lower among adults with 2 or more chronic diseases. Past-year prescription misuse of sedatives (AOR 4.08 [95% CI 2.05-8.12]), stimulants (AOR 3.88 [95% CI 2.00-7.53]), and tranquilizers (AOR 10.02 [95% CI 6.48-15.50]) were all associated with past-year opioid misuse. Characteristics of opioid misusers determined in this study-particularly misuse of other substances-may help determine middle-aged and older adults at risk for prescription opioid misuse.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.