Evidence map›Paper›PMID 30763530›Full record

ArticleCell host & microbe2019

The Innate Sense of Bacteriophages.

Paul L Bollyky, Patrick R Secor

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell host & microbe, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Paul L BollykyStanford University, Stanford, CA, USA.
Patrick R SecorUniversity of Montana, Missoula, MT, USA. Electronic address: patrick.secor@mso.umt.edu.
Stanford University · USSt. Patrick Hospital · US

Funding

Immunization against filamentous bacteriophages to prevent bacterial infectionR01AI138981 · NIAID · UNIVERSITY OF MONTANA · PI EVANS, JAY T. · 2018 to 2022
$5.4M
6 · The paper itself

Abstract

Perturbation of the gut microbiota is associated with inflammatory bowel disease, obesity, and even cancer. In this issue of Cell Host & Microbe, Gogokhia et al. 2019 sought to kill cancer-causing bacteria with bacteriophages. However, the bacteriophages themselves directly stimulated an immune response, which worsened inflammatory bowel disease pathogenesis.

Indexed as

BacteriophagesColitisHumansInflammationInflammatory Bowel DiseasesIntestines

Identifiers

PMID30763530
OpenAlexW2912741918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.