Evidence map›Paper›PMID 30763528›Full record

ArticleJornal de pediatria

Abnormal thymic stromal lymphopoietin expression in the gastrointestinal mucosa of patients with eosinophilic gastroenteritis.

Hongmei Guo, Xiaolan Ji, Guang Yang, Yu Jin

Open access · goldAbstract read
In one paragraph

Article in Jornal de pediatria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Eosinophilic Gastritis/Gastroenteritis.Current gastroenterology reports · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hongmei GuoChildren's Hospital Affiliated to Nanjing Medical University, Department of Gastroenterology, Nanjing, China.
Xiaolan JiChildren's Hospital Affiliated to Nanjing Medical University, Department of Gastroenterology, Nanjing, China.
Guang YangChildren's Hospital Affiliated to Nanjing Medical University, Department of Gastroenterology, Nanjing, China.
Yu JinChildren's Hospital Affiliated to Nanjing Medical University, Department of Gastroenterology, Nanjing, China. Electronic address: jinyuldyy@163.com.
Nanjing Medical University · CNNanjing Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the differential expression of the thymic stromal lymphopoietin isoforms, short and long, and discern their biological implications under eosinophilic gastroenteritis.

methodsThe expression of thymic stromal lymphopoietin and its two isoforms in tissues was assessed by quantitative RT-PCR in healthy controls (n=24) and patients with eosinophilic gastroenteritis (n=17).

resultsThymic stromal lymphopoietin mRNA was significantly reduced in eosinophilic gastroenteritis when compared with healthy controls (p<0.0001). A significantly lower amount of short thymic stromal lymphopoietin mRNA was observed in eosinophilic gastroenteritis when compared with controls (p<0.05), while a significantly higher amount of long thymic stromal lymphopoietin mRNA was observed in eosinophilic gastroenteritis when compared with controls (p<0.05). Peak eosinophilic count is significantly positively correlated with the expression of long thymic stromal lymphopoietin mRNA in the gastrointestinal mucosal of patients with eosinophilic gastroenteritis (r

conclusionsAbnormal mucosal thymic stromal lymphopoietin expression may contribute to gastrointestinal mucosa damage in eosinophilic gastroenteritis.

Indexed as

EnteritisEosinophiliaGastritisCytokinesHumansMucous MembraneThymic Stromal LymphopoietinCytokinesThymic Stromal LymphopoietinEosinophilic gastroenteritisGastroenterite eosinofílicaIsoformasIsoformsLinfopoietina estromal tímicaLinfopoietina estromal tímica curtaLinfopoietina estromal tímica longaLong thymic stromal lymphopoietinShort thymic stromal lymphopoietinThymic stromal lymphopoietin

Identifiers

PMID30763528
PMCPMC9432300
OpenAlexW2914821604

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.