ArticleJournal of medical virology2019
Prevalence and characteristics of acute respiratory virus infections in pediatric cancer patients.
Article in Journal of medical virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- A Systematic Review of Phytochemistry, Pharmacology and Pharmacokinetics onInternational journal of molecular sciences · 2019Pooled it
- Impact of Routine Respiratory Pathogen Panel Test on Outcome of Pediatric Oncology Patients With Febrile Neutropenia.Cancer reports (Hoboken, N.J.) · 2026Article
- The course of respiratory tract infections in pediatric hemato-oncology patients during and after the COVID-19 pandemic: single center retrospective cohort study.Frontiers in pediatrics · 2026Article
- Risk Factors for Severe Outcomes Among Pediatric Cancer Patients with Respiratory Viral Infection.Microorganisms · 2025Article
- Next-Generation Sequencing for Infectious Disease Diagnostics in Pediatric Patients with Malignancies or After Hematopoietic Cell Transplantation: A Systematic Review.Journal of clinical medicine · 2025Review
- Unmasking Pediatric Asthma: Epigenetic Fingerprints and Markers of Respiratory Infections.International journal of molecular sciences · 2025Review
- Frequency and Clinical Outcomes of Respiratory Infections in Children with Cancer Presenting with Febrile Illness.South Asian journal of cancer · 2025Article
- Shifting respiratory pathogens: Post-COVID-19 trends in community-acquired infections in underserved communities.PloS one · 2025Article
- Occurrence of influenza and bacterial infections in cancer patients receiving radiotherapy in Ghana.PloS one · 2022Article
- Usefulness of procalcitonin (PCT), C-reactive protein (CRP), and white blood cell (WBC) levels in the differential diagnosis of acute bacterial, viral, and mycoplasmal respiratory tract infections in children.BMC pulmonary medicine · 2021Article
- SARS-CoV-2 vaccination for adolescents and young adult patients treated at a specialist pediatric oncology unit.Pediatric blood & cancer · 2021Article
- Bacterial and Viral Coinfections with the Human Respiratory Syncytial Virus.Microorganisms · 2021Review
- Hematological manifestations of SARS-CoV-2 in children.Pediatric blood & cancer · 2020Review
- The Management of Children with Cancer during the COVID-19 Pandemic: A Rapid Review.Journal of clinical medicine · 2020Review
- SARS-CoV-2 infections in children and young people.Clinical immunology (Orlando, Fla.) · 2020Review
- SARS-CoV-2 disease and children under treatment for cancer.Pediatric blood & cancer · 2020Article
- Children with cancer in the time of COVID-19: An 8-week report from the six pediatric onco-hematology centers in Lombardia, Italy.Pediatric blood & cancer · 2020Article
- The burden of laboratory-confirmed influenza infection in Lebanon between 2008 and 2016: a single tertiary care center experience.BMC infectious diseases · 2020Article
- Epidemiology and clinical characteristics of viral infections in hospitalized children and adolescents with cancer in Lebanon.PloS one · 2020Article
- Epidemiological characteristics and phylogenic analysis of human respiratory syncytial virus in patients with respiratory infections during 2011-2016 in southern China.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with pediatric cancer have a higher risk of morbidity and mortality because of respiratory viral infections than other patient populations.
objectivesTo investigate the causative viruses of respiratory infections and their burden among patients with pediatric cancer in Lebanon. STUDY
designNasopharyngeal swabs along with clinical and demographic data were collected from patients with pediatric cancer presenting febrile episodes with upper respiratory tract symptoms. Total nucleic acid was extracted from specimens followed by the real-time PCR analysis targeting 14 respiratory viruses to estimate the frequency of infections.
resultsWe obtained 89 nasopharyngeal swabs from patients with pediatric cancer (mean age, 5.8 ± 4.2 years). Real-time PCR confirmed viral infection in 77 swabs (86.5%). Among these, 151 respiratory viruses were detected. Several viruses cocirculated within the same period; respiratory syncytial virus (RSV) being the most common (45.45%), followed by parainfluenza virus (PIV; 26%), influenza type B (26%), human metapneumovirus (24.6%), and human coronavirus (HCoV; 24.6%). Coinfections were detected in 55% of the subjects, and most of them involved RSV with one or more other viruses. A strong correlation was found between PIV, Flu (influenza of any type), RSV, and HCoV with the incidence of coinfections. RSV was associated with lower respiratory tract infections, nasal congestion, bronchitis, and bacteremia. HCoV was associated with bronchiolitis; rhinovirus was associated with hospital admission.
conclusionPatients with pediatric cancer have a high burden of respiratory viral infections and a high incidence of coinfections. Molecular diagnostics can improve management of febrile episodes and reduce antibiotic use.
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