Evidence map›Paper›PMID 30763400›Full record

ArticlePloS one2019

Racial and ethnic disparities in medication adherence among privately insured patients in the United States.

Zhiwen Xie, Patricia St Clair, Dana P Goldman, Geoffrey Joyce

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 2 pooled it
14.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 2 syntheses or guidelines pooled it, 119 citations in OpenAlex.

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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhiwen XieSchaeffer Center for Health Policy & Economics, University of Southern California, Los Angeles, California, United States of America.
Patricia St ClairData Core, Schaeffer Center for Health Policy & Economics, University of Southern California, Los Angeles, California, United States of America.
Dana P GoldmanSchools of Public Policy, Pharmacy, and Economics, University of Southern California, Los Angeles, California, United States of America.ORCID 0000-0001-8498-6396
Geoffrey JoyceDepartment of Pharmaceutical & Health Economics, USC School of Pharmacy, Los Angeles, California, United States of America.
University of Southern California · US

Funding

USC-Yale Roybal Center for Behavioral Interventions in AgingP30AG024968 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JASON N. DOCTOR · 2004 to 2026
$14.7M
USC Resource Center for Minority Aging Research (US-RCMAR)P30AG043073 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI EMMA AGUILA, JENNIFER A AILSHIRE · 2012 to 2026
$10.1M
AN ECONOMIC AND BEHAVIORAL EVALUATION OF MEDICARE PART DP01AG033559 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GOLDMAN, DANA P · 2011 to 2015
$3.0M
Impact of Drug Benefit Design on Utilization and CostR03HS013447 · AHRQ · RAND CORPORATION · PI JOYCE, GEOFFREY F · 2002 to 2002
–
AHRQ HHS R03 HS013447NIA NIH HHS P01 AG033559NIA NIH HHS P30 AG024968NIA NIH HHS P30 AG043073
6 · The paper itself

Abstract

objectiveTo examine the association between socioeconomic status (SES) and racial and ethnic disparities in medication adherence for three widely prescribed therapeutic classes.

methodsWe linked longitudinal claims data from a large US-based insurance provider (2011-2013) to detailed SES information to identify patients treated with oral antidiabetic (N = 56,720), antihypertensive (N = 156,468) or antihyperlipidemic (N = 144,673) medications. We measured adherence and discontinuation by therapeutic class, and conducted regression analysis to quantify the contributions of different factors in the association between race/ethnicity and medication adherence.

resultsDuring an average follow-up period of 2.5 years, average adherence rates of Blacks and Hispanics were at least 7.5 percentage points lower than those of Whites. Controlling for demographics, health status, out-of-pocket costs, convenience of refilling prescriptions and SES attenuated the association by 30 to 50 percent, nonetheless substantial racial disparities persisted (4.1-5.8 percentage points), particularly for asymptomatic conditions. Separating adherence among existing users from those that discontinued therapies indicates that racial/ethnic disparities in adherence reflect inconsistent pill-taking rather than differential rates of discontinuation.

conclusionsRacial/ethnic disparities in adherence are mitigated, but persist after controlling for detailed socioeconomic measures. Interventions should focus more on improving medication adherence of existing users, particularly in treating asymptomatic conditions.

Indexed as

Drug MonitoringInsurance, HealthEthnicityFemaleHumansMaleMiddle AgedRacial GroupsSocial ClassUnited States

Identifiers

PMID30763400
PMCPMC6375669
OpenAlexW2913031074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.