ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2019
Psychosocial stress and C-reactive protein from mid-adolescence to young adulthood.
Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06063174 (Identifying Social, Molecular, & Immunological Processes for Mitigating Toxic Stress & Enhancing Personalized Resilience), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Identifying Social, Molecular, & Immunological Processes for Mitigating Toxic Stress & Enhancing Personalized Resilience
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- The longitudinal associations of inflammatory biomarkers and depression revisited: systematic review, meta-analysis, and meta-regression.Molecular psychiatry · 2021Pooled it
- Interpersonal stress, epigenetic indices of inflammation, and depressive symptoms: Longitudinal associations from adolescence to young adulthood.Neurobiology of stress · 2026Article
- Sex, early life adversity, and negative self-evaluation shape the association between negative life events and depressive symptoms in adolescence.Scientific reports · 2025Article
- Assessing Health Behaviors as Predictors of Psychological Resilience and BMI in a National and Small Military College Sample.Healthcare (Basel, Switzerland) · 2025Article
- Investigating psychosocial factors and systemic inflammation using dried blood spots: a scoping review.Social psychiatry and psychiatric epidemiology · 2025Article
- Relating Biopsychosocial Meanings to Semi-Quantitative CRP Readings Among Primary Healthcare Users: Trends from a Cross-Sectional Study Analysis.Journal of clinical medicine · 2025Article
- Value-based cognitive control moderates the relation of inflammation with depression in adolescents.Social cognitive and affective neuroscience · 2025Article
- Analyzing the Impact of Family Structure Changes on Children's Stress Levels Using a Stress Biomarker.Journal of health and social behavior · 2024Article
- A dyadic longitudinal analysis of parent-adolescent inflammation trends and the role of shared socioeconomic characteristics on family inflammation.Brain, behavior, & immunity - health · 2024Article
- Negative work-to-family spillover stress and heightened cardiovascular risk biomarkers in midlife and older adults.Journal of psychosomatic research · 2024Article
- Association between psychosocial factors and C-reactive protein across income, race, and sex.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024Article
- Affective reactivity to daily stressors and immune cell gene expression in the MIDUS study.Brain, behavior, and immunity · 2024Article
- Emerging Roles of Sodium Glucose Cotransporter 2 (SGLT-2) Inhibitors in Diabetic Cardiovascular Diseases: Focusing on Immunity, Inflammation and Metabolism.Frontiers in pharmacology · 2022Review
- Linking stressful life events and chronic inflammation using suPAR (soluble urokinase plasminogen activator receptor).Brain, behavior, and immunity · 2021Article
- Perceived discrimination predicts elevated biological markers of inflammation among sexual minority adults.Journal of behavioral medicine · 2021Article
- Exposure to adversity and inflammatory outcomes in mid and late childhood.Brain, behavior, & immunity - health · 2020Article
- Sleep and Inflammation During Adolescents' Transition to Young Adulthood.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2020Article
- Persistent Low Positive Affect and Sleep Disturbance across Adolescence Moderate Link between Stress and Depressive Symptoms in Early Adulthood.Journal of abnormal child psychology · 2020Article
- The relationship between body shape perception and health behaviors among Korean normal-weight adolescents using Korea Youth Risk Behavior Web-Based Survey.Journal of exercise rehabilitation · 2019Article
- Psychological Stress During Childhood and Adolescence and Its Association With Inflammation Across the Lifespan: A Critical Review and Meta-Analysis.Psychological bulletinArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveCardiovascular disease (CVD) is one of the most prevalent chronic conditions and leading causes of death. Although CVD clinically manifests in adulthood, underlying processes of CVD begin in the earlier decades of life. Inflammation has been shown to play a key role, but relatively little is understood about how inflammation changes over time among young individuals. Additionally, how psychosocial factors like stress may influence changes in inflammation earlier in the lifespan is not entirely clear. Thus, the current three-wave longitudinal study examined the developmental trajectory of CRP, a marker of systemic inflammation, over a 4-year period from mid-adolescence into young adulthood. Between- and within-person differences in stress in relation to changes in CRP were also examined.
methodA sample of 350 individuals was recruited during mid-adolescence and participated in 1 to 3 assessments, 2 years apart. At each assessment, participants provided dried blood spots for the assessment of CRP and reported on recent major life events, perceived stress, and daily interpersonal stress.
resultsMultilevel modeling indicated that CRP increased with age, and within-person increases in perceived stress, but not life events or daily stress, were associated with higher CRP. Between-person differences in average levels of stress from mid-adolescence into young adulthood were not associated with changes in CRP.
conclusionThese findings suggest that the link between stress and systemic inflammation between mid-adolescence and young adulthood may be most affected by contemporaneous experiences of perceived stress. There was little evidence to suggest that CRP trajectories varied by between-person differences in overall average levels of perceived stress, life events, and daily stress. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.