Evidence map›Paper›PMID 30762243›Full record

ArticleAmerican journal of industrial medicine2019

Factory and construction work is associated with an increased risk of severe lumbar spinal stenosis on MRI: A case control analysis within the wakayama spine study.

Yuyu Ishimoto, Cyrus Cooper, Georgia Ntani, Hiroshi Yamada, Hiroshi Hashizume, Keiji Nagata, Shigeyuki Muraki, Sakae Tanaka, Noriko Yoshimura, Munehito Yoshida and 1 more

Open access · hybridAbstract read
In one paragraph

Article in American journal of industrial medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Yuyu IshimotoMRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, Hampshire, United Kingdom.
Cyrus CooperMRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, Hampshire, United Kingdom.
Georgia NtaniMRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, Hampshire, United Kingdom.
Hiroshi YamadaOrthopedic surgery, Wakayama Medical University, Wakayama city, Wakayama prefecture, Japan.
Hiroshi HashizumeOrthopedic surgery, Wakayama Medical University, Wakayama city, Wakayama prefecture, Japan.
Keiji NagataOrthopedic surgery, Wakayama Medical University, Wakayama city, Wakayama prefecture, Japan.
Shigeyuki MurakiFaculty of Medicine, Department of Preventive Medicine for Locomotive Organ Disorders, 22nd Century Medical & Research Center, University of Tokyo, Tokyo, Japan.
Sakae TanakaDepartment of Orthopedic Surgery, Sensory and Motor System Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Noriko YoshimuraDepartment of Joint Disease Research, 22nd Century Medical and Research Center, University of Tokyo, Tokyo, Japan.
Munehito YoshidaOrthopedic surgery, Wakayama Medical University, Wakayama city, Wakayama prefecture, Japan.
Karen Walker-BoneMRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, Hampshire, United Kingdom.
Wakayama Medical University · JPMRC Lifecourse Epidemiology Unit · GBTokyo Medical University · JPSouthampton General Hospital · GBThe University of Tokyo · JP

Funding

Medical Research Council G0400491Medical Research Council G0601019Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1014Medical Research Council MC_UP_A620_1015Medical Research Council MC_UU_12011/1Medical Research Council MC_UU_12011/2Versus Arthritis 17702
6 · The paper itself

Abstract

backgroundTo explore the association of MRI-diagnosed severe lumbar spinal stenosis with occupation.

methodsOccupational data were collected by questionnaire and all participants underwent spine MRI scans using the same protocol. Central lumbar spinal stenosis (LSS) was graded qualitatively. Those with severe LSS (>two-thirds narrowing) were compared with the controls with lesser degrees of stenosis or no stenosis.

resultsData were available for 722 subjects, mean age 70.1 years. 239 (33%) cases with severe LSS were identified. Factory/construction workers had an almost four-fold increased risk of severe LSS after adjustment for age, sex, smoking, and walking speed amongst those aged <75 years (OR 3.97, 95%CI 1.46-10.85). Severe LSS was also associated with squatting ≥1 h/day (OR 1.76, 95%CI 1.01-3.07) but this association became non-significant after adjustment.

conclusionFurther research is needed but this study adds more evidence that occupational factors are associated with an increased risk and/or severity of degenerative disease of the lumbar spine.

Indexed as

Lumbar VertebraeAgedAged, 80 and overCase-Control StudiesConstruction IndustryFemaleHumansJapanMagnetic Resonance ImagingMaleManufacturing and Industrial FacilitiesMiddle AgedOccupational DiseasesOccupational ExposureRisk FactorsSpinal Stenosisfactory and construction workersLumbar spinal stenosis (LSS)MRIoccupationoccupational exposures

Identifiers

PMID30762243
PMCPMC6499731
OpenAlexW2914324962

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.