Evidence map›Paper›PMID 30762198›Full record

Trial reportLasers in medical science2019

The skin rejuvenation associated treatment-Fraxel laser, Microbotox, and low G prime hyaluronic acid: preliminary results.

Dario Bertossi, Giorgio Giampaoli, Alessandra Lucchese, Maurizio Manuelli, Massimo Albanese, Riccardo Nocini, Pier Francesco Nocini

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Lasers in medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dario BertossiDepartment of Oral and Maxillofacial Surgery, University of Verona, Policlinico G.B. Rossi, Piazzale L. Scuro, 10, 37134, Verona, Italy.
Giorgio GiampaoliDepartment of Oral and Maxillofacial Surgery, University of Verona, Policlinico G.B. Rossi, Piazzale L. Scuro, 10, 37134, Verona, Italy. giorgio.giampaoli@gmail.com.ORCID http://orcid.org/0000-0003-0605-8126
Alessandra LuccheseDepartment of Orthodontics, Vita-Salute San Raffaele University, Milan, Italy.
Maurizio ManuelliDepartment of Orthodontics, Vita-Salute San Raffaele University, Milan, Italy.
Massimo AlbaneseDepartment of Oral and Maxillofacial Surgery, University of Verona, Policlinico G.B. Rossi, Piazzale L. Scuro, 10, 37134, Verona, Italy.
Riccardo NociniENT Department, University of Verona, Verona, Italy.
Pier Francesco NociniDepartment of Oral and Maxillofacial Surgery, University of Verona, Policlinico G.B. Rossi, Piazzale L. Scuro, 10, 37134, Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Minimally invasive facial rejuvenation procedures reached an all-time high in the 2016. This reveals a growing interest in a smoother, younger, and tighter look accessible using the esthetic medicine tools like botulinum toxin and dermal filler injections, laser, and microdermabrasion. Forty-five patients from 35 to 52 years old (medium age 43.8), 38 women and 7 men underwent 5 sessions of Fraxel laser, 1 session of very low G prime HA, and Microbotox injection treatments from January 2016 and January 2017, were included in this study. In this study, we demonstrated that the usage of three treatments together, like mBTX, Volite, and Fractional laser, have a better result despite every single technique alone. The clinical result showed 98% (44 patients, 6 males, 38 females) of the patients had a smoother skin surface, brighter, more hydrated, and elastic skin; 68% of our patients (31 patients, 5 males, 26 females) showed less skin defects and staining as well as less small wrinkles, thanks to Fraxel laser treatment; 98% (44 patients, 6 males, 38 females) showed tighter skin with less sebaceous gland secretion. The aim of this study was to demonstrate that the combination of three techniques acts better and faster than single treatment to contrast facial aging and to improve skin texture and quality.

Indexed as

Cosmetic TechniquesLasersRejuvenationAdultFaceFemaleHumansHyaluronic AcidMaleMiddle AgedSkinSkin AgingHyaluronic AcidFraxelMicrobotoxVery low G prime hyaluronic acid

Identifiers

PMID30762198

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.