Evidence map›Paper›PMID 30762111›Full record

ArticleEuropean radiology2019

Added value of apparent diffusion coefficient in distinguishing between serous and mucin-producing pancreatic cystic neoplasms.

Pallavi Pandey, Ankur Pandey, Nannan Shao, Farnaz Najmi Varzaneh, Mounes Aliyari Ghasabeh, Manijeh Zharghampour, Pegah Khoshpouri, Daniel Fouladi, John Eng, Anne Marie O'Broin-Lennon and 3 more

Abstract read
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In one paragraph

Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Imaging of the Liver and Pancreas: The Added Value of MRI.Diagnostics (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Pallavi PandeyRussell H. Morgan Department of Radiology and Radiological Sciences, Central Radiology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Room 143, Baltimore, MD, 21287, USA.
Ankur PandeyRussell H. Morgan Department of Radiology and Radiological Sciences, Central Radiology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Room 143, Baltimore, MD, 21287, USA.
Nannan ShaoRussell H. Morgan Department of Radiology and Radiological Sciences, Central Radiology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Room 143, Baltimore, MD, 21287, USA.
Farnaz Najmi VarzanehRussell H. Morgan Department of Radiology and Radiological Sciences, Central Radiology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Room 143, Baltimore, MD, 21287, USA.
Mounes Aliyari GhasabehRussell H. Morgan Department of Radiology and Radiological Sciences, Central Radiology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Room 143, Baltimore, MD, 21287, USA.
Manijeh ZharghampourRussell H. Morgan Department of Radiology and Radiological Sciences, Central Radiology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Room 143, Baltimore, MD, 21287, USA.
Pegah KhoshpouriRussell H. Morgan Department of Radiology and Radiological Sciences, Central Radiology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Room 143, Baltimore, MD, 21287, USA.
Daniel FouladiRussell H. Morgan Department of Radiology and Radiological Sciences, Central Radiology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Room 143, Baltimore, MD, 21287, USA.
John EngRussell H. Morgan Department of Radiology and Radiological Sciences, Central Radiology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Room 143, Baltimore, MD, 21287, USA.
Anne Marie O'Broin-LennonDivision of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Marcia CantoDivision of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Ralph H HrubanDepartment of Pathology, Johns Hopkins Medical Institutions, 1550 Orleans Street, Baltimore, MD, 21231, USA.
Ihab R KamelRussell H. Morgan Department of Radiology and Radiological Sciences, Central Radiology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Room 143, Baltimore, MD, 21287, USA. ikamel@jhmi.edu.
Johns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the added value of diffusion-weighted imaging (DWI) on MRI in differentiating serous from mucin-producing pancreatic cystic neoplasms (PCNs).

methodsOne hundred seventeen patients with PCN measuring ≥ 10 mm were included. Three readers independently evaluated MRI with and without the use of apparent diffusion coefficient (ADC). Logistic regression was used to analyze whether confidence scores were different with the use of different image sets. Diagnostic performance with and without ADC was compared.

resultsDWI/ADC improved confidence in 44.8%, 73.6%, and 78.2% of patients by the three readers in distinguishing serous from mucin-producing PCNs. The use of ADC increased the probability of a higher confidence in the differentiation as compared to morphological imaging for all three readers (p < 0.001). Odds ratio for increase in the diagnostic confidence with the use of ADC for the three readers with decreasing years of experience were 5.8, 6.8, and 12.7. The diagnostic accuracy of morphological MRI with ADC was higher than that without ADC for two of three readers with lesser experience (87.2% vs. 80.8%; 91.5% vs. 80.8%).

conclusionDWI may have added value as a complementary tool to conventional morphological MRI in differentiating between serous and mucin-producing PCNs with possibly greater value for readers with less experience in reading abdominal MRI. KEY POINTS: • Optimal management of PCNs requires differentiation of serous from mucin-producing PCNs. • ADC measurements allow increased confidence in differentiating serous from mucin-producing PCNs. • ADC measurements increase the accuracy in diagnosing serous versus mucin-producing PCNs.

Indexed as

AdultAgedAged, 80 and overDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingFemaleHumansMaleMiddle AgedMucinsPancreasPancreatic NeoplasmsReproducibility of ResultsRetrospective StudiesMucinsCystsDiffusion MRIMagnetic resonance imagingMucinPancreas

Identifiers

PMID30762111
OpenAlexW2912184277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.