ArticleTurkish journal of medical sciences2019
Polypharmacy and drug-related problems among people living with HIV/AIDS: a single-center experience
Article in Turkish journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- What is polypharmacy in people living with HIV/AIDS? A systematic review.AIDS research and therapy · 2022Pooled it
- Assessment of drug therapy problems and associated factors among PLWHA and tuberculosis admitted to two referral hospitals in Lusaka, Zambia.BMC infectious diseases · 2026Observational
- Polypharmacy in HIV: Rethinking what counts and why it matters.HIV medicine · 2026Review
- Aging and HIV: Recent Findings in Contributing Factors.AIDS research and treatment · 2025Review
- Polypharmacy and health related quality of life among older adults on antiretroviral therapy in a tertiary hospital in Tanzania: a hospital-based cross-sectional study.BMC infectious diseases · 2023Article
- A retrospective study: Can dual ART mitigate the risk of potential drug-drug interactions among PLWH under stable ART?Turkish journal of medical sciences · 2023Article
- The first nationwide implementation of pharmaceutical care practices through a continuing professional development approach for community pharmacists.International journal of clinical pharmacy · 2022Article
- Sarcopenia in people living with HIV in Hong Kong: which definition correlates with health outcomes?Journal of the International AIDS Society · 2022Article
- Prevalence and global trends of polypharmacy among people living with HIV: a systematic review and meta-analysis.Therapeutic advances in drug safety · 2022Article
- Impact of Clinical Pharmacist-led Interventions in TurkeyTurkish journal of pharmaceutical sciences · 2021Article
- Drug therapy problems identified among patients receiving antiretroviral treatment in a HIV clinic: a prospective study in North Central, Nigeria.The Pan African medical journal · 2021Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/aim: The HIV-infected population is aging, and the concomitant comorbidities increase the likelihood of polypharmacy. There is a scarcity of data for determining drug-related problems in people living with HIV/AIDS (PLWHA). Materials and methods: This cross-sectional study was carried out between 1 September 2015 and 1 July 2016. All patients underwent a face-to-face interview with a clinical pharmacist. PCNE Classification V 7.0 was used classify incident drug-related problems (DRPs). Results: The mean age of the patients was 40.4 ± 13.06 years. The rate of polypharmacy was 66.1% in patients with comorbidities and 12.3% in those without comorbidities (P < 0.001). DRPs were more prominent in older patients (46 vs. 37 years, P < 0.001), those with longer durations of antiretroviral therapy (ART) (45 vs. 27 months, P = 0.014), and those with lower education levels (P = 0.013). Receiving >3 ART drugs was associated with more DRPs in the logistic regression model (odds ratio: 8.299, 95% confidence interval: 1.924–35.803). Fifty-eight interventions were performed in 45 (24.9%) patients. Clinical pharmacist interventions were performed in 18.9% of patients without polypharmacy and in 38.9% of patients with polypharmacy (P < 0.001). Conclusion: DRPs and polypharmacy are common among elderly PLWHA. More interventions are warranted to boost the quality of life in aging PLWHA.
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