ArticleTurkish journal of medical sciences2019
A neglected causative agent in diabetic foot infection: a retrospective evaluation of 13 patients with fungal etiology
Article in Turkish journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Candida Drug Resistance in Patients With Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis.International wound journal · 2026Pooled it
- Investigating the Prevalence of Fungi in Diabetic Ulcers: An Under-Recognised Contributor to Polymicrobial Biofilms.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025Article
- Understanding the multifaceted etiopathogenesis of foot complications in individuals with diabetes.World journal of clinical cases · 2023Review
- 2-Octylcyclopentanone Inhibits Beta Lactam Resistant Diabetic Wound Pathogens.Tropical life sciences research · 2023Article
- A Designed Host Defense Peptide for the Topical Treatment of MRSA-Infected Diabetic Wounds.International journal of molecular sciences · 2023Article
- The effect of comorbid factors and amputation level on mortality in geriatric patients with diabetic foot.Joint diseases and related surgery · 2023Article
- Speciation and antifungal susceptibility ofThe Pan African medical journal · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/aim: Clinicians often neglect fungal infections and do not routinely investigate deep tissue from the wound for fungal culture and sensitivity due to insufficient information in the literature. In this study, we aimed to evaluate fungal etiology of invasive fungal diabetic foot which is rarely reported in the literature. Materials and methods: The patients who were unresponsive to antibiotic therapy and those with positive fungal in bone or deep tissue culture were enrolled in the study. Detailed hospital records were retrieved for demographics and clinical features. Results: A total of 13 patients who were diagnosed with invasive fungal diabetic foot (ten females, three males, mean age 59.8 ± 9 years) were included. All of the patients had type-2 diabetes mellitus. Eleven (84.6%) patients had mixed infection. The most common cause of fungal infections of diabetic foot ulcers was the Candida species. Ten (76.9%) patients underwent amputation, two (15.4%) patients refused amputation, and one patient died before surgery. Conclusion: Invasive fungal infections may also be a causative pathogen in deep tissue infections. Therefore, fungal pathogens should be considered in patients unresponsive to long-term antibiotic therapy. Early detection of fungal infections in high-risk individuals is critical for the prevention of severe consequences such as foot amputation.
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