Evidence map›Paper›PMID 30761774›Full record

ArticleCancer medicine2019

Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance.

Batoul Farran, Samet Albayrak, Judith Abrams, Michael A Tainsky, Nancy K Levin, Robert Morris, Larry H Matherly, Manohar Ratnam, Ira Winer

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Batoul FarranDepartment of Oncology, Wayne State University and Karmanos Cancer Institute, Detroit, Michigan.
Samet AlbayrakDepartment of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan.
Judith AbramsDepartment of Oncology, Wayne State University and Karmanos Cancer Institute, Detroit, Michigan.
Michael A TainskyDepartment of Oncology, Wayne State University and Karmanos Cancer Institute and Center for Molecular Medicine and Genetics, Detroit, Michigan.
Nancy K LevinDepartment of Oncology, Wayne State University and Karmanos Cancer Institute, Detroit, Michigan.
Robert MorrisDepartment of Oncology, Division of Gynecologic Oncology, Wayne State University and Karmanos Cancer Institute, Detroit, Michigan.
Larry H MatherlyDepartments of Oncology and Pharmacology, Wayne State University and Karmanos Cancer Institute, Detroit, Michigan.
Manohar RatnamDepartment of Oncology, Wayne State University and Karmanos Cancer Institute, Detroit, Michigan.
Ira WinerDepartment of Oncology, Division of Gynecologic Oncology, Wayne State University and Karmanos Cancer Institute, Detroit, Michigan.ORCID 0000-0001-6056-8296
Wayne State University · US

Funding

Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI PAUL M STEMMER · 1985 to 2026
$68.4M
Diagnostic Assays for OVCA Recurrence using Paraneoplastic Antigens and EpitopesR21CA187278 · NCI · WAYNE STATE UNIVERSITY · PI TAINSKY, MICHAEL A · 2014 to 2015
$364k
NCI NIH HHS P30 CA022453NCI NIH HHS R21 CA187278
6 · The paper itself

Abstract

Novelty and Impact Statement: Our findings suggest that soluble folate receptor (sFR) could be used in both the initial diagnosis and surveillance of patients with ovarian cancer. Our cohort constitutes one of the largest comparison groups for sFR analyzed so far. We have defined the background level of sFR using healthy volunteers. This is also the first study to prospectively follow patients in the surveillance setting to concurrently identify differential changes in tumor markers CA-125 and sFR.

Indexed as

Biomarkers, TumorCA-125 AntigenCarcinoma, Ovarian EpithelialCase-Control StudiesDisease ProgressionFemaleFolate Receptor 1HumansMembrane ProteinsMiddle AgedNeoplasm StagingPrognosisProspective StudiesBiomarkers, TumorCA-125 AntigenFolate Receptor 1FOLR1 protein, humanMembrane ProteinsMUC16 protein, humanbiomarkersgynecologic oncologytranslational research

Identifiers

PMID30761774
PMCPMC6434204
OpenAlexW2914383831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.