ArticleActa ophthalmologica2019
A new association: acute macular neuroretinopathy in acute optic neuritis.
Article in Acta ophthalmologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- Acute Macular Neuroretinopathy in Association with Orbital Inflammation and Optic Perineuritis.Neuro-ophthalmology (Aeolus Press) · 2026Article
- A case of acute macular neuroretinopathy in a pediatric patient with optic neuritis.American journal of ophthalmology case reports · 2025Article
- MOG antibody-associated optic neuritis.Eye (London, England) · 2024Review
- Paracentral acute middle maculopathy in a patient with Myelin Oligodendrocyte glycoprotein antibody associated optic neuritis.American journal of ophthalmology case reports · 2024Article
- Acute-Onset Retinal Conditions Mimicking Acute Optic Neuritis: Overview and Differential Diagnosis.Journal of clinical medicine · 2023Review
- Paracentral Acute Middle Maculopathy Associated with Severe Anti-Mog (Myelin Oligodendrocyte Glycoprotein)-Positive Optic Neuritis.Neuro-ophthalmology (Aeolus Press) · 2023Article
- Did the COVID-19 Pandemic Increase the Incidence of Acute Macular Neuroretinopathy?Journal of clinical medicine · 2021Article
- Incidence of uveitis and macular edema among patients taking fingolimod 0.5 mg for multiple sclerosis.Journal of ophthalmic inflammation and infection · 2020Article
- Myelin oligodendrocyte glycoprotein antibody-associated optic neuritis: an update.Arquivos brasileiros de oftalmologiaArticle
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7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute optic neuritis (AON) is a common optic nerve disease leading to retrograde degeneration of optic nerve axons, reflected by thinning of the inner retinal layers on optical coherence tomography. On the contrary, acute macular neuroretinopathy (AMN) type 2 is a rare outer retinal disorder that leads to thinning of the outer nuclear layers and is diagnosed by multimodal imaging. The aim of this study was to report a new association between these two diseases.
methodsPatients with a first episode of optic neuritis were invited to participate in a study that involved optical coherence tomography evaluation at baseline and the following 1, 3, 6 and 12 months. All the study patients underwent ophthalmologic evaluation that comprised of visual acuity, visual field and multimodal imaging as well as orbital and brain Magnetic Resonance Imaging. A diagnosis of multiple sclerosis was made according to the 2010 McDonald criteria.
resultsSix of the 114 patients with acute optic neuritis also had acute macular neuroretinopathy, of whom three were positive for myelin oligodendrocyte glycoprotein antibodies (MOG-Abs), two had relapsing-remitting multiple sclerosis and one had clinical isolated syndrome.
conclusionOur study suggests that it is imperative to check for associated AMN in cases of AON, especially those associated with MOG-Abs.
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