Evidence map›Paper›PMID 3076168›Full record

ArticleJournal of anatomy1988

Immuno-electron microscopical localisation of alpha-actinin and actin in microvilli of prostatic epithelial cells.

N Kawai, G Aumüller

Abstract read
In one paragraph

Article in Journal of anatomy, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

N KawaiDepartment of Anatomy, Aichi Medical University, Japan.
G Aumüller
Aichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The localisation of alpha-actinin and actin was investigated immunocytochemically in microvilli of rat ventral prostatic epithelial cells fixed by a solution containing 1.25% glutaraldehyde and 1% paraformaldehyde. Both proteins were localised in the microvilli by immunoperoxidase labelling of semithin or ultrathin sections. Almost the whole microvillous core region was labelled by antibodies for actin. Most of the label for alpha-actinin was confined to the region close to the plasma membrane along the length of the microvilli. In addition, positive staining was found at the microvillous tip and weak staining at a small area in the core. These results suggest a role of alpha-actinin in the stabilisation of actin filaments in these regions.

Indexed as

ActininActinsAnimalsEpitheliumImmunoenzyme TechniquesMaleMicroscopy, ElectronMicrovilliProstateRatsRats, Inbred StrainsActininActins

Identifiers

PMID3076168
PMCPMC1262096
OpenAlexW233550509

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.