Evidence map›Paper›PMID 30761390›Full record

ArticleJournal of immunological sciences2018

Elimination of Epidemic Meningitis in the African Region: Progress and Challenges: 2010-2016.

Amadou Fall, André Fouda Bita, Clement Lingani, Mamoudou Djingarey, Carole Tevi-Benissan, Marie-Pierre Preziosi, Olivier Ronveaux, R Mihigo, J Okeibunor, Bartholomew Dicky Akanmori

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Article in Journal of immunological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amadou FallIST West Africa, WHO Regional Office for Africa, Ougadougou, Burkina Faso.
André Fouda BitaIST West Africa, WHO Regional Office for Africa, Ougadougou, Burkina Faso.
Clement LinganiIST West Africa, WHO Regional Office for Africa, Ougadougou, Burkina Faso.
Mamoudou DjingareyIST West Africa, WHO Regional Office for Africa, Ougadougou, Burkina Faso.
Carole Tevi-BenissanIVD/FRH, WHO Regional Office for Africa, Brazzaville, Congo.
Marie-Pierre PreziosiIVR/IVB WHO HQ, Geneva, Switzerland.
Olivier RonveauxWorld Health Organization. Department: Control of Epidemic Diseases. City: Geneva.
R MihigoIVD/FRH, WHO Regional Office for Africa, Brazzaville, Congo.
J OkeibunorPolio Eradication Programme, WHO Regional Office for Africa, Brazzaville, Congo.
Bartholomew Dicky AkanmoriIVD/FRH, WHO Regional Office for Africa, Brazzaville, Congo.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundEpidemics of meningococcal disease constitute a major public health challenge in Africa, affecting mostly the 24 countries of the meningitis belt. These epidemics led to a call for a call for a safe, effective and affordable conjugate vaccine against the major serogroup responsible for recent epidemics by leaders of the region.

objectiveThis paper documents experiences with efforts at eliminating epidemic meningitis in the African Region.

methodThe meningoccocal serogroup A conjugate vaccine was developed, licensed and offered to more than 235 million people through mass vaccination campaigns in 16 countries since 2010. Future plans include providing the vaccine to the remaining countries in the African Meningitis Belt and, to implement the vaccine into routine national infant immunization programme and to organise catch-up immunization campaigns every 5 years for unvaccinated <5 year-olds who had missed their routine vaccinations.

resultsThe success of the project is evidenced by the large declines in cases of group A meningococcal disease since 2010, with no cases reported in vaccinated persons across the 16 countries, reflecting the highly effective nature of the vaccine. The successful control of serogroup A meningococcal disease has highlighted the need to tackle other meningococcal serogroups through development of polyvalent conjugate vaccines with the aim of eliminating epidemics of meningococcal meningitis in the African region.

Indexed as

African RegionChallengesEliminationEpidemic MeningitisProgress

Identifiers

PMID30761390
PMCPMC6370001

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.